BeCyclOp (BeGC1)

Photoreceptor BeCyclOp (BeGC1)
Binding partner /
Cofactor none
Source organism Blastocladiella emersonii
Mode of action cGMP production
Excitation wavelength 530 nm
Reversion wavelength dark
Excitation time ? Add information
Reversion time ? Add information
Crystal structure of the homodimer of the BeCyclOp guanylyl cyclase domain. Note: the rhodopsin domain is missing. (PDB ID: 6AOB)

Related original publications

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  1. Synthetic Light-Activated Ion Channels for Optogenetic Activation and Inhibition. Front Neurosci, 2018
  2. Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp. Nat Commun, 2015
  3. The rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling. Sci Signal, 2015