PHY domain governs structural and photochemical fidelity in the far-red-absorbing state of phytochromes.
Abstract:
Despite its central role in signaling, the influence of protein architecture on phytochrome structure and reactivity remains poorly understood. Here, we test how removal of the PHY domain reshapes the far-red-absorbing Pfr energy landscape and photochemical branching in the knotless phytochrome All2699g1g2.