Platform on Molecular Optogenetics

OptoBase is an annotated database, which aims to cover all existing not ion-flux based optogenetic switches and publications. It is meant for both expert optogeneticists, to easily keep track of the field, as well as for all researchers who find optogenetics inviting as a powerful tool to address their biological questions of interest.

Latest updates (see all entries)
May 16, 2018 | How to get the most out of your search?

Improve your publication search experience by getting to know our database and learning about the OptoBase-specific syntax, now further explained with a set of helpful examples.

Feb. 21, 2018 | Find The Application

Looking for optogenetic publications presenting a particular type of biological application(s)? The new tool, Find The Application, helps you find them instantly.

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Optogenetic Switches

(see the extended overview of the switches)

Click on a switch for additional information.

BLUF domains

PixD/PixE

LOV domains

AsLOV2 LOVTRAP iLID TULIP AtLOV2 CrLOV1 EL222
FKF1/GI NcWC1-LOV RsLOV VfAU1-LOV VVD Magnets YtvA

Phytochromes

BphP1/PpsR2 BphP1/Q-PAS1
UV Violet Blue Cyan Green Yellow Red Far Red
300 nm 400 nm 500 nm 600 nm 700 nm

UV receptors

UVR8/COP1 UVR8/UVR8

Cryptochromes

CRY2/CIB1 CRY2/CRY2 CRY2clust CRY2olig

Fluorescent Proteins

PYP

Fluorescent proteins

Dronpa145K/N Dronpa145N pdDronpa1

Cobalamin-binding domains

MxCBD TtCBD

Phytochromes

Cph1 PhyA/FHY1 & PhyA/FHL PhyB/PIF3 & PhyB/PIF6