Platform on Molecular Optogenetics

OptoBase is an annotated database, which aims to cover all existing not ion-flux based optogenetic switches and publications. It is meant for both expert optogeneticists, to easily keep track of the field, as well as for all researchers who find optogenetics inviting as a powerful tool to address their biological questions of interest.

Cite as: K. Kolar et al.: OptoBase: A Web Platform for Molecular Optogenetics. ACS Synth. Biol. 2018, DOI: 10.1021/acssynbio.8b00120

News & Updates (see all entries)
June 05, 2021 | The Optogenetics Conference 2021 | Learn more at their website:


June 04, 2021 | Research Highlights in May

Paper of the month May: Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering.

Featured Paper: Learn more about optogenetic tools based on LOV domains: LOVTRAP: an optogenetic system for photoinduced protein dissociation.

Optogenetic Switches

(see the extended overview of the switches)

Click on a switch for additional information.

UV Violet Blue Cyan Green Yellow Red Far Red
300 nm 400 nm 500 nm 600 nm 700 nm

UV receptors


Fluorescent proteins


Fluorescent proteins

Dronpa145K/N Dronpa145N pdDronpa1

Cobalamin-binding domains