Platform on Molecular Optogenetics

OptoBase is an annotated database, which aims to cover all existing not ion-flux based optogenetic switches and publications. It is meant for both expert optogeneticists, to easily keep track of the field, as well as for all researchers who find optogenetics inviting as a powerful tool to address their biological questions of interest.

Cite as: K. Kolar et al.: OptoBase: A Web Platform for Molecular Optogenetics. ACS Synth. Biol. 2018, DOI: 10.1021/acssynbio.8b00120

Latest updates (see all entries)
March 25, 2019 | ** Important info **

Due to some major maintenance work on the power grid behind the hosting server, OptoBase will be temporarily unavailable on Tuesday, 26 March 2019, between 00:01 and 13:00 CET. Thank you for your patience! 

Jan. 13, 2019 | New year, new tool: Glossary

OptoBase has been upgraded with a new tool — Glossary. There you will find brief definitions of various terms and abbreviations commonly used in optogenetics. P.s.: You are most welcome to suggest new terms via our submission form

Optogenetic Switches

(see the extended overview of the switches)

Click on a switch for additional information.

UV Violet Blue Cyan Green Yellow Red Far Red
300 nm 400 nm 500 nm 600 nm 700 nm

UV receptors

UVR8/COP1 UVR8/UVR8

Fluorescent proteins

PYP

Fluorescent proteins

Dronpa145K/N Dronpa145N pdDronpa1

Cobalamin-binding domains

MxCBD TtCBD