Platform on Molecular Optogenetics

OptoBase is an annotated database, which aims to cover all existing non-opsin-based optogenetic switches and publications. It is meant for both expert optogeneticists, to easily keep track of the field, as well as for all researchers who find optogenetics inviting as a powerful tool to address their biological questions of interest.

Cite as: K. Kolar et al.: OptoBase: A Web Platform for Molecular Optogenetics. ACS Synth. Biol. 2018, DOI: 10.1021/acssynbio.8b00120

News & Updates (see all entries)
April 08, 2022 | Research Highlights in March
Feb. 10, 2022 | New tag: Extracellular optogenetics

We constantly adapt optoBase for the latest molecular optogenetic trends. Thus, the new application tag Extracellular optogenetics includes all publications in our database that

  • apply photoreceptors in vitro beyond characterization studies and
  • systems where photoreceptors are expressed on the outer cell surface.

We hope that this new tag streamlines your search on optoBase and welcome suggestions for future tags. Your optoBase-team

Optogenetic Switches

(see the extended overview of the switches)

Click on a switch for additional information.

UV Violet Blue Cyan Green Yellow Red Far Red
300 nm 400 nm 500 nm 600 nm 700 nm

UV receptors


Fluorescent proteins


Fluorescent proteins

Dronpa145K/N Dronpa145N pdDronpa1

Cobalamin-binding domains