Photoreceptor Cph1
Binding partner /
Cofactor PCB
Source organism Synechocystis sp. PCC 6803
Mode of action homodimerization
Excitation wavelength 660 nm
Reversion wavelength 740 nm
Excitation time milliseconds
Reversion time milliseconds
Crystal structure of Cph1, Pr state. (PDB ID: 2VEA)

Related original publications

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  1. A red light-controlled probiotic bio-system for in-situ gut-brain axis regulation. Biomaterials, 2023
  2. Benchmarking of Cph1 Mutants and DrBphP for Light-Responsive Phytochrome-Based Hydrogels with Reversibly Adjustable Mechanical Properties. Adv Biol (Weinh), 2022
  3. Orthogonal Blue and Red Light Controlled Cell-Cell Adhesions Enable Sorting-out in Multicellular Structures. ACS Synth Biol, 2020
  4. Synthesis of a Light-Controlled Phytochrome-Based Extracellular Matrix with Reversibly Adjustable Mechanical Properties. Methods Mol Biol, 2020
  5. Design and Application of Light-Regulated Receptor Tyrosine Kinases. Methods Mol Biol, 2020
  6. Production of Phytochromes by High-Cell-Density E. coli Fermentation. ACS Synth Biol, 2019
  7. Light-Controlled, High-Resolution Patterning of Living Engineered Bacteria Onto Textiles, Ceramics, and Plastic. Adv Funct Mater, 2019
  8. Independent Blue and Red Light Triggered Narcissistic Self-Sorting Self-Assembly of Colloidal Particles. Small, 2019
  9. Rewiring bacterial two-component systems by modular DNA-binding domain swapping. Nat Chem Biol, 2019
  10. Phytochrome-Based Extracellular Matrix with Reversibly Tunable Mechanical Properties. Adv Mater Weinheim, 2019
  11. Re-engineering the two-component systems as light-regulated in Escherichia coli. J Biosci, 2017
  12. Engineering RGB color vision into Escherichia coli. Nat Chem Biol, 2017
  13. A photoconversion model for full spectral programming and multiplexing of optogenetic systems. Mol Syst Biol, 2017
  14. A Phytochrome Sensory Domain Permits Receptor Activation by Red Light. Angew Chem Int Ed Engl, 2016
  15. Refactoring and optimization of light-switchable Escherichia coli two-component systems. ACS Synth Biol, 2014
  16. Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals. Nat Methods, 2014
  17. Multichromatic control of gene expression in Escherichia coli. J Mol Biol, 2010
  18. A synthetic genetic edge detection program. Cell, 2009
  19. Synthetic biology: engineering Escherichia coli to see light. Nature, 2005
  20. Plate-based assays for light-regulated gene expression systems. Meth Enzymol, 2011