Optogenetic Regulation of EphA1 RTK Activation and Signaling. bioRxiv, 2024
A platform to induce and mature biomolecular condensates using chemicals and light. Nat Chem Biol, 2024
Optogenetic-mediated induction and monitoring of α-synuclein aggregation in cellular models of Parkinson's disease. STAR Protoc, 2023
Prior Fc Receptor activation primes macrophages for increased sensitivity to IgG via long term and short term mechanisms. bioRxiv, 2023
Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice. bioRxiv, 2023
Light-induced trapping of endogenous proteins reveals spatiotemporal roles of microtubule and kinesin-1 in dendrite patterning of Drosophila sensory neurons. bioRxiv, 2023
Optogenetic Induction of Pyroptosis, Necroptosis, and Apoptosis in Mammalian Cell Lines. Bio Protoc, 2023
Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape. Cell Syst, 2023
RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration. bioRxiv, 2023
The Opto-inflammasome in zebrafish as a tool to study cell and tissue responses to speck formation and cell death. Elife, 2023
Light-induced condensates show accumulation-prone and less dynamic properties in the nucleus compared to the cytoplasm. bioRxiv, 2023
Optogenetic Activation of Ripk3 Reveals a Thresholding Mechanism in Intracellular and Intercellular Necroptosis. J Comput Soc Sci, 2023
Integration of intermittent calcium signals in T cells revealed by temporally patterned optogenetics. iScience, 2023
DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling. Cell Rep, 2023
Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles. Nat Commun, 2022
Optogenetic control of GGGGCC repeat-containing RNA phase transition. Fundam res, 2022
Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing. Nat Commun, 2022
PPARγ phase separates with RXRα at PPREs to regulate target gene expression. Cell Discov, 2022
Optogenetic activators of apoptosis, necroptosis, and pyroptosis. J Cell Biol, 2022
Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae. J Vis Exp, 2022
WNK kinases sense molecular crowding and rescue cell volume via phase separation. bioRxiv, 2022
Optogenetic Manipulation of Cell Migration with High Spatiotemporal Resolution Using Lattice Lightsheet Microscopy. bioRxiv, 2022
CeLINC, a fluorescence-based protein-protein interaction assay in Caenorhabditis elegans. Genetics, 2021
Activation of endoplasmic reticulum stress via clustering of inner nuclear membrane proteins. bioRxiv, 2021
Optogenetic activators of apoptosis, necroptosis and pyroptosis for probing cell death dynamics and bystander cell responses. bioRxiv, 2021
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy. Mol Cell, 2021
Photon Upconversion Hydrogels for 3D Optogenetics. Adv Funct Mater, 2021
Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase. Neuron, 2018
Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation. Sci Rep, 2018
Optogenetic activation of EphB2 receptor in dendrites induced actin polymerization by activating Arg kinase. Biol Open, 2017
Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2. Nat Commun, 2017
Optogenetic control of the Dab1 signaling pathway. Sci Rep, 2017
Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets. Cell, 2016
An optimized optogenetic clustering tool for probing protein interaction and function. Nat Commun, 2014