CRY2olig

Photoreceptor CRY2olig
Binding partner /
Cofactor FAD
Source organism Arabidopsis thaliana
Mode of action homooligomerization
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time minutes

Related original publications

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  1. Optogenetic modulation of TDP-43 oligomerization fast-forwards ALS-related pathologies in the spinal motor neurons. bioRxiv, 2019
  2. Nucleated transcriptional condensates amplify gene expression. bioRxiv, 2019
  3. Optogenetic inhibition of Delta reveals digital Notch signaling output during tissue differentiation. bioRxiv, 2019
  4. Controlling the material properties and rRNA processing function of the nucleolus using light. Proc Natl Acad Sci USA, 2019
  5. m6A-binding YTHDF proteins promote stress granule formation by modulating phase separation of stress granule proteins. bioRxiv, 2019
  6. Phase separation of 53BP1 determines liquid-like behavior of DNA repair compartments. EMBO J, 2019
  7. LADL: light-activated dynamic looping for endogenous gene expression control. Nat Methods, 2019
  8. Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering. bioRxiv, 2019
  9. Light-based control of metabolic flux through assembly of synthetic organelles. Nat Chem Biol, 2019
  10. The Glycolytic Protein Phosphofructokinase Dynamically Relocalizes into Subcellular Compartments with Liquid-like Properties in vivo. bioRxiv, 2019
  11. NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop. Sci Signal, 2019
  12. RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron, 2019
  13. Light-Induced Protein Clustering for Optogenetic Interference and Protein Interaction Analysis in Drosophila S2 Cells. Biomolecules, 2019
  14. Increasing spatial resolution of photoregulated GTPases through immobilized peripheral membrane proteins. Small GTPases, 2018
  15. Activation of EphB2 Forward Signaling Enhances Memory Consolidation. Cell Rep, 2018
  16. Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase. Neuron, 2018
  17. Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation. Sci Rep, 2018
  18. Optogenetic activation of EphB2 receptor in dendrites induced actin polymerization by activating Arg kinase. Biol Open, 2017
  19. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017
  20. Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2. Nat Commun, 2017
  21. Optogenetic control of the Dab1 signaling pathway. Sci Rep, 2017
  22. Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets. Cell, 2016
  23. An optimized optogenetic clustering tool for probing protein interaction and function. Nat Commun, 2014