Optogenetic control of Wnt signaling for modeling early embryogenic patterning with human pluripotent stem cells. bioRxiv, 2019
Engineering Strategy and Vector Library for the Rapid Generation of Modular Light-Controlled Protein-Protein Interactions. J Mol Biol, 2019
Light-based control of metabolic flux through assembly of synthetic organelles. Nat Chem Biol, 2019
Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology. Elife, 2019
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron, 2019
Continued Activity of the Pioneer Factor Zelda Is Required to Drive Zygotic Genome Activation. Mol Cell, 2019
Intensiometric biosensors visualize the activity of multiple small GTPases in vivo. Nat Commun, 2019
Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome. Cell, 2018
Optogenetic dissection of Rac1 and Cdc42 gradient shaping. Nat Commun, 2018
Optical activation of TrkA signaling. ACS Synth Biol, 2018
Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli. Cell Syst, 2018
Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase. Neuron, 2018
Coupling optogenetics and light-sheet microscopy, a method to study Wnt signaling during embryogenesis. Sci Rep, 2017
Optogenetic control of focal adhesion kinase signaling. Cell Signal, 2017
Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017
Decoding temporal interpretation of the morphogen Bicoid in the early Drosophila embryo. Elife, 2017
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2. Nat Commun, 2017
Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts. Nat Commun, 2017
Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets. Cell, 2016
Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions. Sci Rep, 2016
Using HEK293T Expression System to Study Photoactive Plant Cryptochromes. Front Plant Sci, 2016
Optogenetic activation of axon guidance receptors controls direction of neurite outgrowth. Sci Rep, 2016
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep, 2016
Optogenetic control of endogenous Ca(2+) channels in vivo. Nat Biotechnol, 2015
The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells. ACS Synth Biol, 2015
Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering. Nat Commun, 2015
An optimized optogenetic clustering tool for probing protein interaction and function. Nat Commun, 2014
Spatiotemporal control of fibroblast growth factor receptor signals by blue light. Chem Biol, 2014