Photoreceptor CRY2clust
Binding partner /
Cofactor FAD
Source organism Arabidopsis thaliana
Mode of action homooligomerization
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time minutes

Related original publications

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  1. Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape. Cell Syst, 2023
  2. Advanced human iPSC-based preclinical model for Parkinson's disease with optogenetic alpha-synuclein aggregation. Cell Stem Cell, 2023
  3. Optogenetic Activation of Ripk3 Reveals a Thresholding Mechanism in Intracellular and Intercellular Necroptosis. J Comput Soc Sci, 2023
  4. Light-activated macromolecular phase separation modulates transcription by reconfiguring chromatin interactions. Sci Adv, 2023
  5. Calcium transients trigger switch-like discharge of prostaglandin E2 (PGE2) in an ERK-dependent manner. bioRxiv, 2023
  6. A nucleation barrier spring-loads the CBM signalosome for binary activation. bioRxiv, 2022
  7. Biophysical and biochemical properties of Deup1 self-assemblies: a potential driver for deuterosome formation during multiciliogenesis. Biol Open, 2021
  8. Non-invasive optical control of endogenous Ca2+ channels in awake mice. Nat Commun, 2020
  9. Flotillins promote T cell receptor sorting through a fast Rab5-Rab11 endocytic recycling axis. Nat Commun, 2019
  10. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun, 2018
  11. Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2. Nat Commun, 2017