Magnets

Photoreceptor pMag, nMag
Binding partner /
Cofactor FAD
Source organism Neurospora crassa
Mode of action heterodimerization
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time seconds to hours (variants available)

Related original publications

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  1. Dynamic cybergenetic control of bacterial co-culture composition via optogenetic feedback. Nat Commun, 2022
  2. Implementation of a Novel Optogenetic Tool in Mammalian Cells Based on a Split T7 RNA Polymerase. ACS Synth Biol, 2022
  3. Optogenetic Maxwell Demon to Exploit Intrinsic Noise and Control Cell Differentiation Despite Time Delays and Extrinsic Variability. bioRxiv, 2022
  4. Biochemical noise enables a single optogenetic input to control identical cells to track asymmetric and asynchronous reference signals. bioRxiv, 2022
  5. Dynamic cybergenetic control of bacterial co-culture composition via optogenetic feedback. bioRxiv, 2022
  6. Spatio-temporal, optogenetic control of gene expression in organoids. bioRxiv, 2022
  7. Rapid and robust optogenetic control of gene expression in Drosophila. Dev Cell, 2021
  8. Exploiting Noise, Non-Linearity, and Feedback for Differential Control of Multiple Synthetic Cells with a Single Optogenetic Input. ACS Synth Biol, 2021
  9. Repetitive short-pulsed illumination efficiently activates photoactivatable-Cre as continuous illumination in embryonic stem cells and pre-implantation embryos of transgenic mouse. Genesis, 2021
  10. Optogenetic Tools for Manipulating Protein Subcellular Localization and Intracellular Signaling at Organelle Contact Sites. Curr Protoc, 2021
  11. A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch. Elife, 2021
  12. Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse. Proc Natl Acad Sci U S A, 2020
  13. Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells. Elife, 2020
  14. Optogenetic regulation of embryo implantation in mice using photoactivatable CRISPR-Cas9. Proc Natl Acad Sci U S A, 2020
  15. Exploiting natural chemical photosensitivity of anhydrotetracycline and tetracycline for dynamic and setpoint chemo-optogenetic control. Nat Commun, 2020
  16. Bioluminescence-Triggered Photoswitchable Bacterial Adhesions Enable Higher Sensitivity and Dual-Readout Bacterial Biosensors for Mercury. ACS Sens, 2020
  17. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Nat Commun, 2020
  18. Blue-Light-Switchable Bacterial Cell-Cell Adhesions Enable the Control of Multicellular Bacterial Communities. ACS Synth Biol, 2020
  19. Establishment of a tTA-dependent photoactivatable Cre recombinase knock-in mouse model for optogenetic genome engineering. Biochem Biophys Res Commun, 2020
  20. Light-Inducible Recombinases for Bacterial Optogenetics. ACS Synth Biol, 2020
  21. Engineered BRET-Based Biologic Light Sources Enable Spatiotemporal Control over Diverse Optogenetic Systems. ACS Synth Biol, 2019
  22. The importance of cell-cell interaction dynamics in bottom-up tissue engineering: Concepts of colloidal self-assembly in the fabrication of multicellular architectures. Nano Lett, 2019
  23. High-performance chemical- and light-inducible recombinases in mammalian cells and mice. Nat Commun, 2019
  24. Optogenetic activation of intracellular antibodies for direct modulation of endogenous proteins. Nat Methods, 2019
  25. An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics. ACS Synth Biol, 2019
  26. Near-infrared optogenetic genome engineering based on photon upconversion hydrogels. Angew Chem Int Ed Engl, 2019
  27. A split CRISPR-Cpf1 platform for inducible genome editing and gene activation. Nat Chem Biol, 2019
  28. Photocontrollable mononegaviruses. Proc Natl Acad Sci USA, 2019
  29. Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Nat Commun, 2019
  30. Reversible Social Self-Sorting of Colloidal Cell-Mimics with Blue Light Switchable Proteins. ACS Synth Biol, 2018
  31. Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci USA, 2018
  32. Optogenetic Control of Endoplasmic Reticulum-Mitochondria Tethering. ACS Synth Biol, 2017
  33. Dynamic Blue Light-Inducible T7 RNA Polymerases (Opto-T7RNAPs) for Precise Spatiotemporal Gene Expression Control. ACS Synth Biol, 2017
  34. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods, 2017
  35. Blue Light Switchable Bacterial Adhesion as a Key Step toward the Design of Biofilms. ACS Synth Biol, 2017
  36. Assembly Domain-Based Optogenetic System for the Efficient Control of Cellular Signaling. ACS Synth Biol, 2017
  37. Engineered Photoactivatable Genetic Switches Based on the Bacterium Phage T7 RNA Polymerase. ACS Synth Biol, 2016
  38. Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems. Sci Rep, 2016
  39. A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol, 2016
  40. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol, 2015
  41. Engineered pairs of distinct photoswitches for optogenetic control of cellular proteins. Nat Commun, 2015
  42. Optical Control of Genome Editing by Photoactivatable Cas9. Methods Mol Biol, 2021
  43. Optogenetic Activation of Intracellular Nanobodies. Methods Mol Biol, 2022
  44. Engineered Cas9 extracellular vesicles as a novel gene editing tool. J Extracell Vesicles, 2022