Magnets

Photoreceptor pMag, nMag
Binding partner /
Cofactor FAD
Source organism Neurospora crassa
Mode of action heterodimerization
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time seconds to hours (variants available)

Related original publications

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  1. High-performance chemical- and light-inducible recombinases in mammalian cells and mice. Nat Commun, 2019
  2. Optogenetic activation of intracellular antibodies for direct modulation of endogenous proteins. Nat Methods, 2019
  3. An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics. ACS Synth Biol, 2019
  4. Light-Inducible Recombinases for Bacterial Optogenetics. bioRxiv, 2019
  5. Near-infrared optogenetic genome engineering based on photon upconversion hydrogels. Angew Chem Int Ed Engl, 2019
  6. High-performance chemical and light-inducible recombinases in mammalian cells and mice. bioRxiv, 2019
  7. A split CRISPR-Cpf1 platform for inducible genome editing and gene activation. Nat Chem Biol, 2019
  8. Photocontrollable mononegaviruses. Proc Natl Acad Sci USA, 2019
  9. Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Nat Commun, 2019
  10. Reversible Social Self-Sorting of Colloidal Cell-Mimics with Blue Light Switchable Proteins. ACS Synth Biol, 2018
  11. Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci USA, 2018
  12. Optogenetic Control of Endoplasmic Reticulum-Mitochondria Tethering. ACS Synth Biol, 2017
  13. Dynamic Blue Light-Inducible T7 RNA Polymerases (Opto-T7RNAPs) for Precise Spatiotemporal Gene Expression Control. ACS Synth Biol, 2017
  14. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods, 2017
  15. Blue Light Switchable Bacterial Adhesion as a Key Step toward the Design of Biofilms. ACS Synth Biol, 2017
  16. Assembly Domain-Based Optogenetic System for the Efficient Control of Cellular Signaling. ACS Synth Biol, 2017
  17. Engineered Photoactivatable Genetic Switches Based on the Bacterium Phage T7 RNA Polymerase. ACS Synth Biol, 2016
  18. Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems. Sci Rep, 2016
  19. A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol, 2016
  20. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol, 2015
  21. Engineered pairs of distinct photoswitches for optogenetic control of cellular proteins. Nat Commun, 2015