Magnets

Photoreceptor pMag, nMag
Binding partner /
Cofactor FAD
Source organism Neurospora crassa
Mode of action heterodimerization
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time seconds to hours (variants available)

Related original publications

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  1. Implementation of a novel optogenetic tool in mammalian cells based on a split T7 RNA polymerase. bioRxiv, 2021
  2. Repetitive short-pulsed illumination efficiently activates photoactivatable-Cre as continuous illumination in embryonic stem cells and pre-implantation embryos of transgenic mouse. Genesis, 2021
  3. Optogenetic perturbations of RNA expression in tissue space. bioRxiv, 2021
  4. Optogenetic Tools for Manipulating Protein Subcellular Localization and Intracellular Signaling at Organelle Contact Sites. Curr Protoc, 2021
  5. A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch. Elife, 2021
  6. Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse. Proc Natl Acad Sci U S A, 2020
  7. Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells. Elife, 2020
  8. Optogenetic regulation of embryo implantation in mice using photoactivatable CRISPR-Cas9. Proc Natl Acad Sci U S A, 2020
  9. Exploiting natural chemical photosensitivity of anhydrotetracycline and tetracycline for dynamic and setpoint chemo-optogenetic control. Nat Commun, 2020
  10. Bioluminescence-Triggered Photoswitchable Bacterial Adhesions Enable Higher Sensitivity and Dual-Readout Bacterial Biosensors for Mercury. ACS Sens, 2020
  11. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Nat Commun, 2020
  12. Blue-Light-Switchable Bacterial Cell-Cell Adhesions Enable the Control of Multicellular Bacterial Communities. ACS Synth Biol, 2020
  13. Establishment of a tTA-dependent photoactivatable Cre recombinase knock-in mouse model for optogenetic genome engineering. Biochem Biophys Res Commun, 2020
  14. Light-Inducible Recombinases for Bacterial Optogenetics. ACS Synth Biol, 2020
  15. Engineered BRET-Based Biologic Light Sources Enable Spatiotemporal Control over Diverse Optogenetic Systems. ACS Synth Biol, 2019
  16. The importance of cell-cell interaction dynamics in bottom-up tissue engineering: Concepts of colloidal self-assembly in the fabrication of multicellular architectures. Nano Lett, 2019
  17. High-performance chemical- and light-inducible recombinases in mammalian cells and mice. Nat Commun, 2019
  18. Optogenetic activation of intracellular antibodies for direct modulation of endogenous proteins. Nat Methods, 2019
  19. An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics. ACS Synth Biol, 2019
  20. Near-infrared optogenetic genome engineering based on photon upconversion hydrogels. Angew Chem Int Ed Engl, 2019
  21. A split CRISPR-Cpf1 platform for inducible genome editing and gene activation. Nat Chem Biol, 2019
  22. Photocontrollable mononegaviruses. Proc Natl Acad Sci USA, 2019
  23. Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Nat Commun, 2019
  24. Reversible Social Self-Sorting of Colloidal Cell-Mimics with Blue Light Switchable Proteins. ACS Synth Biol, 2018
  25. Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci USA, 2018
  26. Optogenetic Control of Endoplasmic Reticulum-Mitochondria Tethering. ACS Synth Biol, 2017
  27. Dynamic Blue Light-Inducible T7 RNA Polymerases (Opto-T7RNAPs) for Precise Spatiotemporal Gene Expression Control. ACS Synth Biol, 2017
  28. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods, 2017
  29. Blue Light Switchable Bacterial Adhesion as a Key Step toward the Design of Biofilms. ACS Synth Biol, 2017
  30. Assembly Domain-Based Optogenetic System for the Efficient Control of Cellular Signaling. ACS Synth Biol, 2017
  31. Engineered Photoactivatable Genetic Switches Based on the Bacterium Phage T7 RNA Polymerase. ACS Synth Biol, 2016
  32. Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems. Sci Rep, 2016
  33. A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol, 2016
  34. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol, 2015
  35. Engineered pairs of distinct photoswitches for optogenetic control of cellular proteins. Nat Commun, 2015
  36. Optical Control of Genome Editing by Photoactivatable Cas9. Methods Mol Biol, 2021