Photoreceptor BphP1
Binding partner Q-PAS1
Cofactor Biliverdin
Source organism Rhodopseudomonas palustris
Mode of action heterodimerization
Excitation wavelength 760 nm
Reversion wavelength 641 nm (faster), dark (slower)
Excitation time seconds
Reversion time seconds
Crystal structure of a point mutated (C20S) BphP1 photoreceptor, without Q-PAS1. Note: no wild type structure available at the moment. (PDB ID: 4XTQ)

Related original publications

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  1. A red light-responsive photoswitch for deep tissue optogenetics. Nat Biotechnol, 2022
  2. Smart-watch-programmed green-light-operated percutaneous control of therapeutic transgenes. Nat Commun, 2021
  3. Changes in tongue-palatal contact during swallowing in patients with skeletal mandibular prognathism after orthognathic surgery. PLoS ONE, 2021
  4. Optogenetic regulation of endogenous proteins. Nat Commun, 2020
  5. Near-infrared light-controlled systems for gene transcription regulation, protein targeting and spectral multiplexing. Nat Protoc, 2018
  6. Near-infrared light-controlled gene expression and protein targeting in neurons and non-neuronal cells. Chembiochem, 2018
  7. Optogenetic Control of Endoplasmic Reticulum-Mitochondria Tethering. ACS Synth Biol, 2017
  8. Near-infrared optogenetic pair for protein regulation and spectral multiplexing. Nat Chem Biol, 2017