BphS

Photoreceptor BphS
Binding partner /
Cofactor Biliverdin
Source organism Rhodobacter sphaeroides, Synechocystis sp. Slr1143
Mode of action c-di-GMP production
Excitation wavelength 660 nm
Reversion wavelength 760 nm
Excitation time ? Add information
Reversion time ? Add information
Add a new 3D structure

BphS-derived switches:

Related original publications

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  1. Engineering a 660 nm-Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy. Adv Sci (Weinh), 2026
  2. Improving the Response of Microbial Fuel Cell-Based Biosensing through Optogenetic Enhancement of Electroactive Biofilms. Environ Sci Technol, 2025
  3. Antidiabetic Close Loop Based on Wearable DNA-Hydrogel Glucometer and Implantable Optogenetic Cells. JACS Au, 2024
  4. A programmable protease-based protein secretion platform for therapeutic applications. Nat Chem Biol, 2023
  5. Remotely Controllable Engineered Bacteria for Targeted Therapy of Pseudomonas aeruginosa Infection. ACS Synth Biol, 2023
  6. Programming the lifestyles of engineered bacteria for cancer therapy. Natl Sci Rev, 2023
  7. Measurement of Secreted Embryonic Alkaline Phosphatase. Bio Protoc, 2023
  8. Optogenetic-controlled immunotherapeutic designer cells for post-surgical cancer immunotherapy. Nat Commun, 2022
  9. An adaptive tracking illumination system for optogenetic control of single bacterial cells. Appl Microbiol Biotechnol, 2022
  10. A Self-Powered Optogenetic System for Implantable Blood Glucose Control. Research (Wash D C), 2022
  11. Far-Red Light Triggered Production of Bispecific T Cell Engagers (BiTEs) from Engineered Cells for Antitumor Application. ACS Synth Biol, 2022
  12. A far-red light-inducible CRISPR-Cas12a platform for remote-controlled genome editing and gene activation. Sci Adv, 2021
  13. Far-red light-activated human islet-like designer cells enable sustained fine-tuned secretion of insulin for glucose control. Mol Ther, 2021
  14. A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice. Nat Commun, 2020
  15. Engineering a far-red light–activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors. Sci Adv, 2020
  16. Light-powered Escherichia coli cell division for chemical production. Nat Commun, 2020
  17. Optogenetic modulation of a catalytic biofilm for biotransformation of indole into tryptophan. ChemSusChem, 2019
  18. Engineering a light-responsive, quorum quenching biofilm to mitigate biofouling on water purification membranes. Sci Adv, 2018
  19. Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation. Proc Natl Acad Sci USA, 2018
  20. Bioprinting Living Biofilms through Optogenetic Manipulation. ACS Synth Biol, 2018
  21. Using Light-Activated Enzymes for Modulating Intracellular c-di-GMP Levels in Bacteria. Methods Mol Biol, 2017
  22. Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice. Sci Transl Med, 2017
  23. Optogenetic Module for Dichromatic Control of c-di-GMP Signaling. J Bacteriol, 2017
  24. Optogenetic manipulation of c-di-GMP levels reveals the role of c-di-GMP in regulating aerotaxis receptor activity in Azospirillum brasilense. J Bacteriol, 2017
  25. Near-infrared light responsive synthetic c-di-GMP module for optogenetic applications. ACS Synth Biol, 2014
  26. Constructing a Smartphone-Controlled Semiautomatic Theranostic System for Glucose Homeostasis in Diabetic Mice. Methods Mol Biol, 2021
  27. Constructing Smartphone-Controlled Optogenetic Switches in Mammalian Cells. Methods Mol Biol, 2021