AtLOV2

Photoreceptor AtLOV2
Binding partner /
Cofactor FMN
Source organism Arabidopsis thaliana
Mode of action intramolecular conformational change
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time tens of seconds
Crystal structure of AtLOV2. (PDB ID: 4EEP)

Related original publications

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  1. Development of a Synthetic Switch to Control Protein Stability in Eukaryotic Cells with Light. Methods Mol Biol, 2017
  2. Controlling Protein Activity and Degradation Using Blue Light. Methods Mol Biol, 2016
  3. A photosensitive degron enables acute light-induced protein degradation in the nervous system. Curr Biol, 2015
  4. Photo-sensitive degron variants for tuning protein stability by light. BMC Syst Biol, 2014
  5. Spatio-temporally precise activation of engineered receptor tyrosine kinases by light. EMBO J, 2014
  6. A LOV2 domain-based optogenetic tool to control protein degradation and cellular function. Chem Biol, 2013