TULIP

Photoreceptor LOVpep (AsLOV2–ePDZpeptide)
Binding partner ePDZ
Cofactor FMN
Source organism Avena sativa
Mode of action heterodimerization
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time seconds to minutes (variants available)

Related original publications

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  1. The effect of substrate stiffness on tensile force transduction in the epithelial monolayers. bioRxiv, 2021
  2. Light-inducible deformation of mitochondria in live cells. Cell Chem Biol, 2021
  3. Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude. bioRxiv, 2021
  4. Asymmetric Contraction of Adherens Junctions arises through RhoA and E-cadherin feedback. bioRxiv, 2021
  5. Physically asymmetric division of the C. elegans zygote ensures invariably successful embryogenesis. Elife, 2021
  6. Blue Light‐Operated CRISPR/Cas13b‐Mediated mRNA Knockdown (Lockdown). Adv Biol, 2021
  7. Correction to Lancet Infectious Diseases 2020; published online April 29. https://doi.org/10.1016/ S1473-3099(20)30064-5. Lancet Infect Dis, 2020
  8. Nano-positioning and tubuline conformation determine transport of mitochondria along microtubules. bioRxiv, 2020
  9. RhoA Mediates Epithelial Cell Shape Changes via Mechanosensitive Endocytosis. Dev Cell, 2019
  10. SapTrap Assembly of Caenorhabditis elegans MosSCI Transgene Vectors. G3 (Bethesda), 2019
  11. Mechanosensitive junction remodelling promotes robust epithelial morphogenesis. Lancet Diabetes Endocrinol, 2019
  12. Neurotrophin receptor tyrosine kinases regulated with near-infrared light. Nat Commun, 2019
  13. Guided by light: optogenetic control of microtubule gliding assays. Nano Lett, 2018
  14. Adherens junction-associated pores mediate the intercellular transport of endosomes and cytoplasmic proteins. Biochem Biophys Res Commun, 2018
  15. Optogenetic dissection of mitotic spindle positioning in vivo. Elife, 2018
  16. An Optogenetic approach to control protein localization during embryogenesis of the sea urchin. Dev Biol, 2018
  17. Engaging myosin VI tunes motility, morphology, and identity in endocytosis. Traffic, 2018
  18. Optogenetic interrogation of integrin αVβ3 function in endothelial cells. J Cell Sci, 2017
  19. Cell cycle entry triggers a switch between two modes of Cdc42 activation during yeast polarization. Elife, 2017
  20. Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres. Nat Commun, 2017
  21. A Phytochrome-Derived Photoswitch for Intracellular Transport. ACS Synth Biol, 2017
  22. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun, 2017
  23. Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage. J Cell Biol, 2016
  24. Light-controlled intracellular transport in Caenorhabditis elegans. Curr Biol, 2016
  25. Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. ACS Synth Biol, 2015
  26. Optogenetic control of organelle transport and positioning. Nature, 2015
  27. Benchmarking of optical dimerizer systems. ACS Synth Biol, 2014
  28. Orthogonal optogenetic triple-gene control in Mammalian cells. ACS Synth Biol, 2014
  29. TULIPs: tunable, light-controlled interacting protein tags for cell biology. Nat Methods, 2012
  30. Optogenetic Control of RhoA to Probe Subcellular Mechanochemical Circuitry. Curr Protoc Cell Biol, 2020