TULIP

Photoreceptor LOVpep (AsLOV2–ePDZpeptide)
Binding partner ePDZ
Cofactor FMN
Source organism Avena sativa
Mode of action heterodimerization
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time seconds to minutes (variants available)

Related original publications

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  1. Nano-positioning and tubuline conformation determine transport of mitochondria along microtubules. bioRxiv, 2020
  2. RhoA Mediates Epithelial Cell Shape Changes via Mechanosensitive Endocytosis. Dev Cell, 2019
  3. SapTrap Assembly of Caenorhabditis elegans MosSCI Transgene Vectors. G3 (Bethesda), 2019
  4. Mechanosensitive junction remodelling promotes robust epithelial morphogenesis. Lancet Diabetes Endocrinol, 2019
  5. Neurotrophin receptor tyrosine kinases regulated with near-infrared light. Nat Commun, 2019
  6. Guided by light: optogenetic control of microtubule gliding assays. Nano Lett, 2018
  7. Adherens junction-associated pores mediate the intercellular transport of endosomes and cytoplasmic proteins. Biochem Biophys Res Commun, 2018
  8. Optogenetic dissection of mitotic spindle positioning in vivo. Elife, 2018
  9. An Optogenetic approach to control protein localization during embryogenesis of the sea urchin. Dev Biol, 2018
  10. Engaging myosin VI tunes motility, morphology, and identity in endocytosis. Traffic, 2018
  11. Optogenetic interrogation of integrin αVβ3 function in endothelial cells. J Cell Sci, 2017
  12. Cell cycle entry triggers a switch between two modes of Cdc42 activation during yeast polarization. Elife, 2017
  13. Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres. Nat Commun, 2017
  14. A Phytochrome-Derived Photoswitch for Intracellular Transport. ACS Synth Biol, 2017
  15. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun, 2017
  16. Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage. J Cell Biol, 2016
  17. Light-controlled intracellular transport in Caenorhabditis elegans. Curr Biol, 2016
  18. Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. ACS Synth Biol, 2015
  19. Optogenetic control of organelle transport and positioning. Nature, 2015
  20. Benchmarking of optical dimerizer systems. ACS Synth Biol, 2014
  21. Orthogonal optogenetic triple-gene control in Mammalian cells. ACS Synth Biol, 2014
  22. TULIPs: tunable, light-controlled interacting protein tags for cell biology. Nat Methods, 2012
  23. Optogenetic Control of RhoA to Probe Subcellular Mechanochemical Circuitry. Curr Protoc Cell Biol, 2020