TULIP

Photoreceptor LOVpep (AsLOV2–ePDZpeptide)
Binding partner ePDZ
Cofactor FMN
Source organism Avena sativa
Mode of action heterodimerization
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time seconds to minutes (variants available)

Related original publications

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  1. Adherens junction-associated pores mediate the intercellular transport of endosomes and cytoplasmic proteins. Biochem Biophys Res Commun, 2018
  2. Optogenetic dissection of mitotic spindle positioning in vivo. Elife, 2018
  3. An Optogenetic approach to control protein localization during embryogenesis of the sea urchin. Dev Biol, 2018
  4. Engaging myosin VI tunes motility, morphology, and identity in endocytosis. Traffic, 2018
  5. Optogenetic interrogation of integrin αVβ3 function in endothelial cells. J Cell Sci, 2017
  6. Cell cycle entry triggers a switch between two modes of Cdc42 activation during yeast polarization. Elife, 2017
  7. Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres. Nat Commun, 2017
  8. A Phytochrome-Derived Photoswitch for Intracellular Transport. ACS Synth Biol, 2017
  9. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun, 2017
  10. Light-controlled intracellular transport in Caenorhabditis elegans. Curr Biol, 2016
  11. Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. ACS Synth Biol, 2015
  12. Optogenetic control of organelle transport and positioning. Nature, 2015
  13. Benchmarking of optical dimerizer systems. ACS Synth Biol, 2014
  14. Orthogonal optogenetic triple-gene control in Mammalian cells. ACS Synth Biol, 2014
  15. TULIPs: tunable, light-controlled interacting protein tags for cell biology. Nat Methods, 2012