Photoreceptor DrBphP
Binding partner /
Cofactor Biliverdin
Source organism Deinococcus radiodurans
Mode of action homodimerization, dissociation
Excitation wavelength 660 nm
Reversion wavelength 780 nm, dark
Excitation time ? Add information
Reversion time ? Add information
Crystal structure of DrBphP, Pr state. (PDB ID: 4O0P)

DrBphP-derived switches:

Related original publications

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  1. Optogenetic Control of Bacterial Expression by Red Light. ACS Synth Biol, 2022
  2. A red light-responsive photoswitch for deep tissue optogenetics. Nat Biotechnol, 2022
  3. A general approach for engineering RTKs optically controlled with far-red light. Nat Methods, 2022
  4. Benchmarking of Cph1 Mutants and DrBphP for Light-Responsive Phytochrome-Based Hydrogels with Reversibly Adjustable Mechanical Properties. Adv Biol (Weinh), 2022
  5. Changes in tongue-palatal contact during swallowing in patients with skeletal mandibular prognathism after orthognathic surgery. PLoS ONE, 2021
  6. Creating Red Light-Switchable Protein Dimerization Systems as Genetically Encoded Actuators with High Specificity. ACS Synth Biol, 2020
  7. Bacterial Phytochrome as a Scaffold for Engineering of Receptor Tyrosine Kinases Controlled with Near-Infrared Light. J Mol Biol, 2020
  8. Focusing light inside live tissue using reversibly switchable bacterial phytochrome as a genetically encoded photochromic guide star. Sci Adv, 2019
  9. Revisiting and Redesigning Light-Activated Cyclic-Mononucleotide Phosphodiesterases. J Mol Biol, 2019
  10. Neurotrophin receptor tyrosine kinases regulated with near-infrared light. Nat Commun, 2019
  11. Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications. J Biol Chem, 2018