Photoreceptor BcLOV4
Binding partner /
Cofactor FMN
Source organism Botrytis cinerea
Mode of action intramolecular conformational change, membrane recruitment
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time minutes

Related original publications

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  1. Optogenetic clustering and membrane translocation of the BcLOV4 photoreceptor. bioRxiv, 2022
  2. Computational framework for single-cell spatiotemporal dynamics of optogenetic membrane recruitment. Cell Rep Methods, 2022
  3. Designing Single-Component Optogenetic Membrane Recruitment Systems: The Rho-Family GTPase Signaling Toolbox. ACS Synth Biol, 2022
  4. Temperature-responsive optogenetic probes of cell signaling. Nat Chem Biol, 2021
  5. Single-Component Optogenetic Tools for Inducible RhoA GTPase Signaling. Adv Biol (Weinh), 2021
  6. Single-component optogenetic tools for inducible RhoA GTPase signaling. bioRxiv, 2021
  7. Optogenetic Rac1 engineered from membrane lipid-binding RGS-LOV for inducible lamellipodia formation. Photochem Photobiol Sci, 2020
  8. Synthetic cell-like membrane interfaces for probing dynamic protein-lipid interactions. Meth Enzymol, 2019
  9. Directly light-regulated binding of RGS-LOV photoreceptors to anionic membrane phospholipids. Proc Natl Acad Sci USA, 2018