PAL

Photoreceptor PAL
Binding partner /
Cofactor FMN
Source organism Nakamurella multipartita
Mode of action RNA aptamer binding, translation control
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time ? Add information
Reversion time tens of minutes
Crystal structure of PAL. (PDB ID: 6HMJ)

Related original publications

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  1. Light-Dependent Control of Bacterial Expression at the mRNA Level. ACS Synth Biol, 2022
  2. Optogenetic Control of Bacterial Expression by Red Light. ACS Synth Biol, 2022
  3. Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins. Nat Biotechnol, 2022
  4. Aptamer-Mediated Reversible Transactivation of Gene Expression by Light. Angew Chem Int Ed Engl, 2020
  5. Optoribogenetic control of regulatory RNA molecules. Nat Commun, 2020
  6. A blue light receptor that mediates RNA binding and translational regulation. Nat Chem Biol, 2019