PAL

Photoreceptor PAL
Binding partner /
Cofactor FMN
Source organism Nakamurella multipartita
Mode of action RNA aptamer binding, translation control
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time ? Add information
Reversion time tens of minutes
Crystal structure of PAL. (PDB ID: 6HMJ)

Related original publications

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  1. Leveraging the histidine kinase-phosphatase duality to sculpt two-component signaling. Nat Commun, 2024
  2. Epstein-Barr Virus Promotes Tumorigenicity and Worsens Hodgkin Lymphoma Prognosis by Activating JAK/STAT and NF-κB Signaling Pathways. Iran J Med Sci, 2024
  3. An RNA Motif That Enables Optozyme Control and Light-Dependent Gene Expression in Bacteria and Mammalian Cells. Adv Sci (Weinh), 2024
  4. Light-Dependent Control of Bacterial Expression at the mRNA Level. ACS Synth Biol, 2022
  5. Optogenetic Control of Bacterial Expression by Red Light. ACS Synth Biol, 2022
  6. Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins. Nat Biotechnol, 2022
  7. Aptamer-Mediated Reversible Transactivation of Gene Expression by Light. Angew Chem Int Ed Engl, 2020
  8. Optoribogenetic control of regulatory RNA molecules. Nat Commun, 2020
  9. A blue light receptor that mediates RNA binding and translational regulation. Nat Chem Biol, 2019
  10. Multimodal Control of Bacterial Gene Expression by Red and Blue Light. Methods Mol Biol, 2024