CRY2/CIB1

Related original publications

1. Near-infrared-inducible Bcl-2-associated X protein system for apoptosis regulation in vivo. J Chem Eng, 2023
2. Polarized branched Actin modulates cortical mechanics to produce unequal-size daughters during asymmetric division. Nat Cell Biol, 2023
3. Cell size and actin architecture determine force generation in optogenetically activated cells. Biophys J, 2023
4. Golgi screen identifies the RhoGEF Solo as a novel regulator of RhoB and endocytic transport. Traffic, 2022
5. Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles. Nat Commun, 2022
6. An Optogenetic-Controlled Cell Reprogramming System for Driving Cell Fate and Light-Responsive Chimeric Mice. Adv Sci (Weinh), 2022
7. Precision super-resolution cryo-correlative light and electron microscopy for rapid in situ structural analyses of optogenetically-positioned organelles. bioRxiv, 2022
8. Patterned mechanical feedback establishes a global myosin gradient. Nat Commun, 2022
9. Direct activation of the Ras-Akt network mediates polarity and organizes protrusions in human neutrophil migration. bioRxiv, 2022
10. Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation. Cell Chem Biol, 2022
11. Stable Transgenic Mouse Strain with Enhanced Photoactivatable Cre Recombinase for Spatiotemporal Genome Manipulation. Adv Sci (Weinh), 2022
12. Activity-based directed evolution of a membrane editor in mammalian cells. bioRxiv, 2022
13. Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis. Dev Cell, 2022
14. LITOS: a versatile LED illumination tool for optogenetic stimulation. Sci Rep, 2022
15. Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts. Nat Commun, 2022
16. Automatic detection of spatio-temporal signalling patterns in cell collectives. bioRxiv, 2022
17. Distinct glycerophospholipids potentiate Gsα-activated adenylyl cyclase activity. Cell Signal, 2022
18. Precise control of microtubule disassembly in living cells. EMBO J, 2022
19. Force propagation between epithelial cells depends on active coupling and mechano-structural polarization. bioRxiv, 2022
20. Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration. bioRxiv, 2022
21. Light-dependent modulation of protein localization and function in living bacteria cells. bioRxiv, 2022
22. Light-induced fermenter production of derivatives of the sweet protein monellin is maximized in prestationary Saccharomyces cerevisiae cultures. Biotechnol J, 2022
23. Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition. J Cell Sci, 2022
24. An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins. J Biol Chem, 2022
25. Optogenetic Control of PIP2 Interactions Shaping ENaC Activity. Int J Mol Sci, 2022
26. Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis. bioRxiv, 2022
27. The cell polarity determinant Dlg1 facilitates epithelial invagination by promoting tissue-scale mechanical coordination. Development, 2022
28. Cell size and actin architecture determine force generation in optogenetically activated adherent cells. bioRxiv, 2022
29. Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms. bioRxiv, 2022
30. Spatio-temporal, optogenetic control of gene expression in organoids. bioRxiv, 2022
31. Mechanical strain stimulates COPII-dependent trafficking via Rac1. bioRxiv, 2022
32. Light-driven biological actuators to probe the rheology of 3D microtissues. bioRxiv, 2022
33. Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins. Nat Biotechnol, 2022
34. Optogenetic Manipulation of Cell Migration with High Spatiotemporal Resolution Using Lattice Lightsheet Microscopy. bioRxiv, 2022
35. Cell polarity determinant Dlg1 facilitates epithelial invagination by promoting tissue-scale mechanical coordination. bioRxiv, 2021
36. CeLINC, a fluorescence-based protein-protein interaction assay in Caenorhabditis elegans. Genetics, 2021
37. Optogenetic dissection of the roles of actomyosin in the mechanics underlying tissue fluidity. bioRxiv, 2021
38. Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety. Nat Nanotechnol, 2021
39. Microtubule disassembly by caspases is the rate-limiting step of cell extrusion bioRxiv, 2021
40. Precise control of microtubule disassembly in living cells. bioRxiv, 2021
41. An active tethering mechanism controls the fate of vesicles. Nat Commun, 2021
42. Revisiting the Role of TGFβ Receptor Internalization for Smad Signaling: It is Not Required in Optogenetic TGFβ Signaling Systems. Adv Biol (Weinh), 2021
43. Optogenetic Tools for Control of Public Goods in Saccharomyces cerevisiae. mSphere, 2021
44. Mapping the dynamic transfer functions of eukaryotic gene regulation. Cell Syst, 2021
45. Mechanical worrying drives cell migration in crowded environments. bioRxiv, 2021
46. Rab11 endosomes coordinate centrosome number and movement following mitotic exit. bioRxiv, 2021
47. Using optogenetics to link myosin patterns to contractile cell behaviors during convergent extension. Biophys J, 2021
48. Light-inducible deformation of mitochondria in live cells. Cell Chem Biol, 2021
49. Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival. Dev Cell, 2021
50. Exosome-based delivery of super-repressor IκBα ameliorates kidney ischemia-reperfusion injury. Kidney Int, 2021
51. Optogenetic Control of the Canonical Wnt Signaling Pathway During Xenopus laevis Embryonic Development. J Mol Biol, 2021
52. Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude. bioRxiv, 2021
53. Cell patterning by secretion-induced plasma membrane flows. bioRxiv, 2021
54. PIP2 regulation of TRPC5 channel activation and desensitization. J Biol Chem, 2021
55. Optogenetic relaxation of actomyosin contractility uncovers mechanistic roles of cortical tension during cytokinesis. bioRxiv, 2021
56. Cell division in tissues enables macrophage infiltration. bioRxiv, 2021
57. Optogenetic-based Localization of Talin to the Plasma Membrane Promotes Activation of β3 Integrins. J Biol Chem, 2021
58. A modular tool to query and inducibly disrupt biomolecular condensates. Nat Commun, 2021
59. A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch. Elife, 2021
60. CRISPR-dcas9 Optogenetic Nanosystem for the Blue Light-Mediated Treatment of Neovascular Lesions. ACS Appl Bio Mater, 2021
61. Transient light-activated gene expression in Chinese hamster ovary cells. BMC Biotechnol, 2021
62. A CRISPR-Cas9-Based Near-Infrared Upconversion-Activated DNA Methylation Editing System. ACS Appl Mater Interfaces, 2021
63. Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation. bioRxiv, 2021
64. A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice. Nat Commun, 2021
65. Control of SRC molecular dynamics encodes distinct cytoskeletal responses by specifying signaling pathway usage. J Cell Sci, 2021
66. Optogenetic Control of Phosphatidylinositol (3,4,5)‐triphosphate Production by Light‐sensitive Cryptochrome Proteins on the Plasma Membrane. Chin J Chem, 2021
67. Random sub-diffusion and capture of genes by the nuclear pore reduces dynamics and coordinates interchromosomal movement. bioRxiv, 2021
68. Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. J Biol Chem, 2021
69. Living materials with programmable functionalities grown from engineered microbial co-cultures. Nat Mater, 2021
70. Synthetic gene networks recapitulate dynamic signal decoding and differential gene expression. bioRxiv, 2021
71. A Light-Inducible Split-dCas9 System for Inhibiting the Progression of Bladder Cancer Cells by Activating p53 and E-cadherin. Front Mol Biosci, 2021
72. Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice. Sci Adv, 2021
73. Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse. Proc Natl Acad Sci U S A, 2020
74. Regulating enzymatic reactions in Escherichia coli utilizing light-responsive cellular compartments based on liquid-liquid phase separation. bioRxiv, 2020
75. Spatio-temporal Control of ERK Pulse Frequency Coordinates Fate Decisions during Mammary Acinar Morphogenesis. bioRxiv, 2020
76. Single-Protein Tracking to Study Protein Interactions During Integrin-Based Migration. Methods Mol Biol, 2020
77. Light-inducible Deformation of Mitochondria in Live Cells. bioRxiv, 2020
78. Mechanical competition alters the cellular interpretation of an endogenous genetic programme. bioRxiv, 2020
79. Multichromatic Control of Signaling Pathways in Mammalian Cells. Adv Biosyst, 2020
80. Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila. Elife, 2020
81. Control of Cell Migration Using Optogenetics. Methods Mol Biol, 2020
82. Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast. Cells, 2020
83. CL6mN: Rationally Designed Optogenetic Photoswitches with Tunable Dissociation Dynamics. ACS Synth Biol, 2020
84. A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice. Nat Commun, 2020
85. Photo-SNAP-tag, a Light-Regulated Chemical Labeling System. ACS Chem Biol, 2020
86. Optogenetic Control of Gene Expression Using Cryptochrome 2 and a Light-Activated Degron. Methods Mol Biol, 2020
87. βH-spectrin is required for ratcheting apical pulsatile constrictions during tissue invagination. EMBO Rep, 2020
88. Early But Not Delayed Optogenetic RAF Activation Promotes Astrocytogenesis in Mouse Neural Progenitors. J Mol Biol, 2020
89. Photoactivatable RNA N6 -Methyladenosine Editing with CRISPR-Cas13. Small, 2020
90. Dual Function of PI(4,5)P2 in Insulin-Regulated Exocytic Trafficking of GLUT4 in Adipocytes. J Mol Biol, 2020
91. ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization. Dev Cell, 2020
92. CofActor: A light- and stress-gated optogenetic clustering tool to study disease-associated cytoskeletal dynamics in living cells. J Biol Chem, 2020
93. Optical Activation of TrkB Signaling. J Mol Biol, 2020
94. CLIC4 is a cytokinetic cleavage furrow protein that regulates cortical cytoskeleton stability during cell division. J Cell Sci, 2020
95. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Nat Commun, 2020
96. Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation. Sci Adv, 2020
97. Phosphatidylinositol 4,5-bisphosphate directly interacts with the β and γ subunits of the sodium channel ENaC. J Biol Chem, 2020
98. Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality. Sci Adv, 2020
99. A Generalizable Optogenetic Strategy to Regulate Receptor Tyrosine Kinases during Vertebrate Embryonic Development. J Mol Biol, 2020
100. Cytokinetic bridge triggers de novo lumen formation in vivo. Nat Commun, 2020
101. Tissue-Scale Mechanical Coupling Reduces Morphogenetic Noise to Ensure Precision during Epithelial Folding. Dev Cell, 2020
102. Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds. J Cell Biol, 2020
103. Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation. J Cell Biol, 2020
104. Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling. Nat Commun, 2020
105. Engineering light-controllable CAR T cells for cancer immunotherapy. Sci Adv, 2020
106. Pulsatile MAPK Signaling Modulates p53 Activity to Control Cell Fate Decisions at the G2 Checkpoint for DNA Damage. Cell Rep, 2020
107. Optogenetic control of mRNA localization and translation in live cells. Nat Cell Biol, 2020
108. Cell and tissue manipulation with ultrashort infrared laser pulses in light-sheet microscopy. Sci Rep, 2020
109. Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase. PLoS Biol, 2020
110. Shape-morphing living composites. Sci Adv, 2020
111. Tunable light and drug induced depletion of target proteins. Nat Commun, 2020
112. Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines. Sci Adv, 2020
113. Engineered BRET-Based Biologic Light Sources Enable Spatiotemporal Control over Diverse Optogenetic Systems. ACS Synth Biol, 2019
114. Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Dev Cell, 2019
115. Directed evolution improves the catalytic efficiency of TEV protease. Nat Methods, 2019
116. Blue light-triggered optogenetic system for treating uveal melanoma. Oncogene, 2019
117. A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae. Biotechnol Bioeng, 2019
118. Optogenetic inhibition of Delta reveals digital Notch signaling output during tissue differentiation. EMBO Rep, 2019
119. Imaging of Morphological and Biochemical Hallmarks of Apoptosis with Optimized Optogenetic Actuators. PLoS ONE, 2019
120. Flotillins promote T cell receptor sorting through a fast Rab5-Rab11 endocytic recycling axis. Nat Commun, 2019
121. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat Biotechnol, 2019
122. FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics. Nat Methods, 2019
123. Secretory Vesicle Clustering in Fungal Filamentous Cells Does Not Require Directional Growth. Cell Rep, 2019
124. Light-Induced Transcription Activation for Time-Lapse Microscopy Experiments in Living Cells. Methods Mol Biol, 2019
125. Transient Activations of Rac1 at the Lamellipodium Tip Trigger Membrane Protrusion. Curr Biol, 2019
126. Optogenetic gene editing in regional skin. Cell Res, 2019
127. Achieving tight control of a photoactivatable Cre recombinase gene switch: new design strategies and functional characterization in mammalian cells and rodent. Nucleic Acids Res, 2019
128. Cross-linker-mediated regulation of actin network organization controls tissue morphogenesis. J Cell Biol, 2019
129. LADL: light-activated dynamic looping for endogenous gene expression control. Nat Methods, 2019
130. OpEn-Tag-A Customizable Optogenetic Toolbox To Dissect Subcellular Signaling. ACS Synth Biol, 2019
131. Accurate manipulation of optogenetic proteins with wavelength tunable femtosecond laser system. J Appl Phys, 2019
132. Reversible Optogenetic Control of Growth Factor Signaling During Cell Differentiation and Vertebrate Embryonic Development. OSA Technical Digest, 2019
133. Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos. Cell, 2019
134. Cortical mitochondria regulate insulin secretion by local Ca2+ buffering. J Cell Sci, 2019
135. Advances in optogenetic regulation of gene expression in mammalian cells using cryptochrome 2 (CRY2). Methods, 2019
136. Optogenetic perturbation of the biochemical pathways that control cell behavior. Meth Enzymol, 2019
137. Design, construction, and validation of optogenetic proteins. Lancet Diabetes Endocrinol, 2019
138. Physical Plasma Membrane Perturbation Using Subcellular Optogenetics Drives Integrin-Activated Cell Migration. ACS Synth Biol, 2019
139. Light-Induced Protein Clustering for Optogenetic Interference and Protein Interaction Analysis in Drosophila S2 Cells. Biomolecules, 2019
140. Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem. Biomaterials, 2019
141. A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission. Neuron, 2019
142. Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Nat Commun, 2019
143. Blue Light Switchable Cell–Cell Interactions Provide Reversible and Spatiotemporal Control Towards Bottom-Up Tissue Engineering. Adv Biosyst, 2019
144. Enhanced intrinsic CYP3A4 activity in human hepatic C3A cells with optically controlled CRISPR/dCas9 activator complex. Integr Biol (Camb), 2018
145. Development of a Wireless-Controlled LED Array for the Tunable Optogenetic Control of Cellular Activities. Engineering, 2018
146. Optogenetic dissection of Rac1 and Cdc42 gradient shaping. Nat Commun, 2018
147. Downregulation of basal myosin-II is required for cell shape changes and tissue invagination. EMBO J, 2018
148. Membrane dynamics induced by a PIP3 optogenetic tool. Anal Sci, 2018
149. Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control. Cell, 2018
150. RalB directly triggers invasion downstream Ras by mobilizing the Wave complex. Elife, 2018
151. Light Control of the Tet Gene Expression System in Mammalian Cells. Cell Rep, 2018
152. Optogenetic control of epithelial-mesenchymal transition in cancer cells. Sci Rep, 2018
153. A Single-Component Optogenetic System Allows Stringent Switch of Gene Expression in Yeast Cells. ACS Synth Biol, 2018
154. Spatiotemporal control of zebrafish (Danio rerio) gene expression using a light-activated CRISPR activation system. Gene, 2018
155. Optical activation of TrkA signaling. ACS Synth Biol, 2018
156. Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation. Proc Natl Acad Sci USA, 2018
157. Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis. Nat Commun, 2018
158. Independent Control over Multiple Cell Types in Space and Time Using Orthogonal Blue and Red Light Switchable Cell Interactions. Adv Sci, 2018
159. A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging. Sci Rep, 2018
160. Regulation of cell cycle progression by cell-cell and cell-matrix forces. Nat Cell Biol, 2018
161. Optogenetic inhibition of Gαq protein signaling reduces calcium oscillation stochasticity. ACS Synth Biol, 2018
162. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun, 2018
163. Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation. Sci Rep, 2018
164. A biochemical network controlling basal myosin oscillation. Nat Commun, 2018
165. Optogenetic Control of Cell Migration. Methods Mol Biol, 2018
166. Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci USA, 2018
167. Generation of Optogenetically Modified Adenovirus Vector for Spatiotemporally Controllable Gene Therapy. ACS Chem Biol, 2018
168. Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers. Sci Rep, 2018
169. Spatiotemporal Control of TGF-β Signaling with Light. ACS Synth Biol, 2017
170. Gradients of Rac1 Nanoclusters Support Spatial Patterns of Rac1 Signaling. Cell Rep, 2017
171. Real-time observation of light-controlled transcription in living cells. J Cell Sci, 2017
172. Optogenetic regulation of artificial microRNA improves H2 production in green alga Chlamydomonas reinhardtii. Biotechnol Biofuels, 2017
173. Propagating Wave of ERK Activation Orients Collective Cell Migration. Dev Cell, 2017
174. Near-Infrared Light Triggered Upconversion Optogenetic Nanosystem for Cancer Therapy. ACS Nano, 2017
175. Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase. Cell Chem Biol, 2017
176. Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1. Nucleic Acids Res, 2017
177. A single-chain photoswitchable CRISPR-Cas9 architecture for light-inducible gene editing and transcription. ACS Chem Biol, 2017
178. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017
179. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods, 2017
180. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration. J Biol Chem, 2017
181. Photo-Activatable Akt Probe - A New Tool to Study the Akt-Dependent Physiopathology of Cancer Cells. Oncol Res, 2017
182. An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis. ACS Synth Biol, 2017
183. Vesicle Docking Is a Key Target of Local PI(4,5)P2 Metabolism in the Secretory Pathway of INS-1 Cells. Cell Rep, 2017
184. A calcium- and light-gated switch to induce gene expression in activated neurons. Nat Biotechnol, 2017
185. Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts. Nat Commun, 2017
186. Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development. J Vis Exp, 2017
187. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res, 2017
188. Cell-matrix adhesion and cell-cell adhesion differentially control basal myosin oscillation and Drosophila egg chamber elongation. Nat Commun, 2017
189. Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain. Nat Methods, 2017
190. Light-Regulated Protein Kinases Based on the CRY2-CIB1 System. Methods Mol Biol, 2017
191. Optogenetic control of cellular forces and mechanotransduction. Nat Commun, 2017
192. Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics. Sci Rep, 2017
193. Optogenetic Control of Synaptic Composition and Function. Neuron, 2017
194. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun, 2017
195. A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation. ACS Chem Biol, 2016
196. Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis. Cell Rep, 2016
197. Optogenetic inhibition of apical constriction during Drosophila embryonic development. Methods Cell Biol, 2016
198. An open-hardware platform for optogenetics and photobiology. Sci Rep, 2016
199. A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol, 2016
200. Reversible optogenetic control of kinase activity during differentiation and embryonic development. Development, 2016
201. Optogenetic regulation of site-specific subtelomeric DNA methylation. Oncotarget, 2016
202. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module. Nat Commun, 2016
203. Using HEK293T Expression System to Study Photoactive Plant Cryptochromes. Front Plant Sci, 2016
204. The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress. PLoS ONE, 2016
205. Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action. J Cell Sci, 2016
206. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat Chem Biol, 2016
207. Optogenetic oligomerization of Rab GTPases regulates intracellular membrane trafficking. Nat Chem Biol, 2016
208. Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep, 2016
209. Frequency and amplitude control of cortical oscillations by phosphoinositide waves. Nat Chem Biol, 2016
210. An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis. Dev Cell, 2015
211. Predictive Spatiotemporal Manipulation of Signaling Perturbations Using Optogenetics. Biophys J, 2015
212. Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. ACS Synth Biol, 2015
213. An optogenetic system for interrogating the temporal dynamics of Akt. Sci Rep, 2015
214. Optogenetic Control of Gene Expression in Drosophila. PLoS ONE, 2015
215. Photo-activatable Cre recombinase regulates gene expression in vivo. Sci Rep, 2015
216. Optogenetic apoptosis: light-triggered cell death. Angew Chem Int Ed Engl, 2015
217. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol, 2015
218. The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells. ACS Synth Biol, 2015
219. Optogenetic control of molecular motors and organelle distributions in cells. Chem Biol, 2015
220. A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. Nat Chem Biol, 2015
221. CRISPR-Cas9-based photoactivatable transcription system. Chem Biol, 2015
222. Optogenetic control of organelle transport and positioning. Nature, 2015
223. Single-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signaling. Proc Natl Acad Sci USA, 2015
224. Benchmarking of optical dimerizer systems. ACS Synth Biol, 2014
225. Engineered UV-A light-responsive gene expression system for measuring sun cream efficacy in mammalian cell culture. J Biotechnol, 2014
226. Optogenetic engineering: light-directed cell motility. Angew Chem Int Ed Engl, 2014
227. Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration. Mol Biol Cell, 2014
228. Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling. Nat Commun, 2014
229. Reversible protein inactivation by optogenetic trapping in cells. Nat Methods, 2014
230. Bidirectional regulation of mRNA translation in mammalian cells by using PUF domains. Angew Chem Int Ed Engl, 2014
231. Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth. PLoS ONE, 2014
232. Real-time optogenetic control of intracellular protein concentration in microbial cell cultures. Integr Biol (Camb), 2014
233. Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation. Mol Cell, 2013
234. Light-inducible activation of target mRNA translation in mammalian cells. Chem Commun (Camb), 2013
235. Optical control of mammalian endogenous transcription and epigenetic states. Nature, 2013
236. Optogenetic control of PIP3: PIP3 is sufficient to induce the actin-based active part of growth cones and is regulated via endocytosis. PLoS ONE, 2013
237. Live imaging of multicolor-labeled cells in Drosophila. Development, 2013
238. Optogenetic control of transcription in zebrafish. PLoS ONE, 2012
239. Light-mediated control of DNA transcription in yeast. Methods, 2012
240. Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci USA, 2012
241. Rapid blue-light-mediated induction of protein interactions in living cells. Nat Methods, 2010
242. Quantitative Analysis of Membrane Receptor Trafficking Manipulated by Optogenetic Tools. Methods Mol Biol, 2021
243. Engineered Cas9 extracellular vesicles as a novel gene editing tool. J Extracell Vesicles, 2022
244. Optogenetic Methods to Control Tissue Mechanics in Drosophila. Methods Mol Biol, 2022
245. Optogenetic Control of Membrane Trafficking Using Light-Activated Reversible Inhibition by Assembly Trap of Intracellular Membranes (IM-LARIAT). Methods Mol Biol, 2022