CRY2/CIB1

Related original publications

1. The Dystrophin-Dystroglycan complex ensures cytokinesis efficiency in Drosophila epithelia. bioRxiv, 2024
2. Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivity. bioRxiv, 2024
3. Epithelial folding through local degradation of an elastic basement membrane plate. bioRxiv, 2024
4. Temporal dynamics of BMP/Nodal ratio drive tissue-specific gastrulation morphogenesis. bioRxiv, 2024
5. Enhancing high-throughput optogenetics: Integration of LITOS with Lustro enables simultaneous light stimulation and shaking. MicroPubl Biol, 2024
6. Using split protein reassembly strategy to optically control PLD enzymatic activity. bioRxiv, 2024
7. Ultralow Background Membrane Editors for Spatiotemporal Control of Phosphatidic Acid Metabolism and Signaling ACS Cent Sci, 2024
8. Optogenetic generation of leader cells reveals a force-velocity relation for collective cell migration. bioRxiv, 2024
9. Development of an optogenetics tool, Opto-RANK, for control of osteoclast differentiation using blue light. Sci Rep, 2024
10. A mechanical wave travels along a genetic guide to drive the formation of an epithelial furrow during Drosophila gastrulation. Dev Cell, 2024
11. A platform to induce and mature biomolecular condensates using chemicals and light. Nat Chem Biol, 2024
12. Bidirectional Allosteric Coupling between PIP2 Binding and the Pore of the Oncochannel TRPV6. Int J Mol Sci, 2024
13. Optogenetic induction of caspase-8 mediated apoptosis by employing Arabidopsis cryptochrome 2. Sci Rep, 2023
14. Dynamic Multiplexed Control and Modeling of Optogenetic Systems Using the High-Throughput Optogenetic Platform, Lustro. bioRxiv, 2023
15. Liebig’s law of the minimum in the TGF-β/SMAD pathway. bioRxiv, 2023
16. A single-component, light-assisted uncaging switch for endoproteolytic release. Nat Chem Biol, 2023
17. A programmable protease-based protein secretion platform for therapeutic applications. Nat Chem Biol, 2023
18. AAV-compatible optogenetic tools for activating endogenous calcium channels in vivo. Mol Brain, 2023
19. Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice. bioRxiv, 2023
20. Light-induced trapping of endogenous proteins reveals spatiotemporal roles of microtubule and kinesin-1 in dendrite patterning of Drosophila sensory neurons. bioRxiv, 2023
21. Spatiotemporal, optogenetic control of gene expression in organoids. Nat Methods, 2023
22. Photoactivatable base editors for spatiotemporally controlled genome editing in vivo. Biomaterials, 2023
23. Diya – a universal light illumination platform for multiwell plate cultures. iScience, 2023
24. Cell Cycle Control by Optogenetically Regulated Cell Cycle Inhibitor Protein p21. Biology (Basel), 2023
25. Spatiotemporal optical control of Gαq-PLCβ interactions. bioRxiv, 2023
26. High-Throughput Optogenetics Experiments in Yeast Using the Automated Platform Lustro. J Vis Exp, 2023
27. Optogenetic strategies for optimizing the performance of biosensors of membrane phospholipids in live cells. bioRxiv, 2023
28. Lustro: High-Throughput Optogenetic Experiments Enabled by Automation and a Yeast Optogenetic Toolkit. ACS Synth Biol, 2023
29. Optogenetic control of Cdc48 for dynamic metabolic engineering in yeast. Metab Eng, 2023
30. Mechanosensitive dynamics of lysosomes along microtubules regulate leader cell emergence in collective cell migration. bioRxiv, 2023
31. Concept and considerations of a medical device: the active noise cancelling incubator. Front Pediatr, 2023
32. An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells. Nat Commun, 2023
33. Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair. J Nanobiotechnology, 2023
34. Optogenetic Activation of Ripk3 Reveals a Thresholding Mechanism in Intracellular and Intercellular Necroptosis. J Comput Soc Sci, 2023
35. Activity-based directed evolution of a membrane editor in mammalian cells. Nat Chem, 2023
36. Actuation of single downstream nodes in growth factor network steers immune cell migration. Dev Cell, 2023
37. Rab8, Rab11, and Rab35 coordinate lumen and cilia formation during zebrafish left-right organizer development. PLoS Genet, 2023
38. OptIC Notch reveals mechanism that regulates receptor interactions with CSL. Development, 2023
39. Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling. Cell Rep, 2023
40. Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation. bioRxiv, 2023
41. Light Activated BioID (LAB): an optically activated proximity labeling system to study protein-protein interactions. bioRxiv, 2023
42. Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos. J Vis Exp, 2023
43. Optogenetic decoding of Akt2-regulated metabolic signaling pathways in skeletal muscle cells using transomics analysis. Sci Signal, 2023
44. Near-infrared-inducible Bcl-2-associated X protein system for apoptosis regulation in vivo. J Chem Eng, 2023
45. Polarized branched Actin modulates cortical mechanics to produce unequal-size daughters during asymmetric division. Nat Cell Biol, 2023
46. Cell size and actin architecture determine force generation in optogenetically activated cells. Biophys J, 2023
47. An optogenetic tool to inhibit RhoA in Drosophila embryos. STAR Protoc, 2023
48. Golgi screen identifies the RhoGEF Solo as a novel regulator of RhoB and endocytic transport. Traffic, 2022
49. Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles. Nat Commun, 2022
50. An Optogenetic-Controlled Cell Reprogramming System for Driving Cell Fate and Light-Responsive Chimeric Mice. Adv Sci (Weinh), 2022
51. Precision super-resolution cryo-correlative light and electron microscopy for rapid in situ structural analyses of optogenetically-positioned organelles. bioRxiv, 2022
52. Patterned mechanical feedback establishes a global myosin gradient. Nat Commun, 2022
53. Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation. Cell Chem Biol, 2022
54. Stable Transgenic Mouse Strain with Enhanced Photoactivatable Cre Recombinase for Spatiotemporal Genome Manipulation. Adv Sci (Weinh), 2022
55. Activity-based directed evolution of a membrane editor in mammalian cells. bioRxiv, 2022
56. Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis. Dev Cell, 2022
57. LITOS: a versatile LED illumination tool for optogenetic stimulation. Sci Rep, 2022
58. Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts. Nat Commun, 2022
59. Automatic detection of spatio-temporal signalling patterns in cell collectives. bioRxiv, 2022
60. Distinct glycerophospholipids potentiate Gsα-activated adenylyl cyclase activity. Cell Signal, 2022
61. Precise control of microtubule disassembly in living cells. EMBO J, 2022
62. Force propagation between epithelial cells depends on active coupling and mechano-structural polarization. bioRxiv, 2022
63. Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration. bioRxiv, 2022
64. Light-dependent modulation of protein localization and function in living bacteria cells. bioRxiv, 2022
65. Light-induced fermenter production of derivatives of the sweet protein monellin is maximized in prestationary Saccharomyces cerevisiae cultures. Biotechnol J, 2022
66. Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition. J Cell Sci, 2022
67. An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins. J Biol Chem, 2022
68. Optogenetic Control of PIP2 Interactions Shaping ENaC Activity. Int J Mol Sci, 2022
69. Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis. bioRxiv, 2022
70. The cell polarity determinant Dlg1 facilitates epithelial invagination by promoting tissue-scale mechanical coordination. Development, 2022
71. Cell size and actin architecture determine force generation in optogenetically activated adherent cells. bioRxiv, 2022
72. Optogenetic inhibition of actomyosin reveals mechanical bistability of the mesoderm epithelium during Drosophila mesoderm invagination. Elife, 2022
73. Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms. bioRxiv, 2022
74. Spatio-temporal, optogenetic control of gene expression in organoids. bioRxiv, 2022
75. Mechanical strain stimulates COPII-dependent trafficking via Rac1. bioRxiv, 2022
76. Light-driven biological actuators to probe the rheology of 3D microtissues. bioRxiv, 2022
77. Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins. Nat Biotechnol, 2022
78. Optogenetic Manipulation of Cell Migration with High Spatiotemporal Resolution Using Lattice Lightsheet Microscopy. bioRxiv, 2022
79. Cell polarity determinant Dlg1 facilitates epithelial invagination by promoting tissue-scale mechanical coordination. bioRxiv, 2021
80. CeLINC, a fluorescence-based protein-protein interaction assay in Caenorhabditis elegans. Genetics, 2021
81. Optogenetic dissection of the roles of actomyosin in the mechanics underlying tissue fluidity. bioRxiv, 2021
82. Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety. Nat Nanotechnol, 2021
83. Microtubule disassembly by caspases is the rate-limiting step of cell extrusion bioRxiv, 2021
84. Precise control of microtubule disassembly in living cells. bioRxiv, 2021
85. An active tethering mechanism controls the fate of vesicles. Nat Commun, 2021
86. Revisiting the Role of TGFβ Receptor Internalization for Smad Signaling: It is Not Required in Optogenetic TGFβ Signaling Systems. Adv Biol (Weinh), 2021
87. Optogenetic Tools for Control of Public Goods in Saccharomyces cerevisiae. mSphere, 2021
88. Mapping the dynamic transfer functions of eukaryotic gene regulation. Cell Syst, 2021
89. Mechanical worrying drives cell migration in crowded environments. bioRxiv, 2021
90. Rab11 endosomes coordinate centrosome number and movement following mitotic exit. bioRxiv, 2021
91. Using optogenetics to link myosin patterns to contractile cell behaviors during convergent extension. Biophys J, 2021
92. Light-inducible deformation of mitochondria in live cells. Cell Chem Biol, 2021
93. Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival. Dev Cell, 2021
94. Exosome-based delivery of super-repressor IκBα ameliorates kidney ischemia-reperfusion injury. Kidney Int, 2021
95. Optogenetic Control of the Canonical Wnt Signaling Pathway During Xenopus laevis Embryonic Development. J Mol Biol, 2021
96. Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude. bioRxiv, 2021
97. Cell patterning by secretion-induced plasma membrane flows. bioRxiv, 2021
98. PIP2 regulation of TRPC5 channel activation and desensitization. J Biol Chem, 2021
99. Optogenetic relaxation of actomyosin contractility uncovers mechanistic roles of cortical tension during cytokinesis. bioRxiv, 2021
100. Cell division in tissues enables macrophage infiltration. bioRxiv, 2021
101. Optogenetic-based Localization of Talin to the Plasma Membrane Promotes Activation of β3 Integrins. J Biol Chem, 2021
102. A modular tool to query and inducibly disrupt biomolecular condensates. Nat Commun, 2021
103. A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch. Elife, 2021
104. CRISPR-dcas9 Optogenetic Nanosystem for the Blue Light-Mediated Treatment of Neovascular Lesions. ACS Appl Bio Mater, 2021
105. Transient light-activated gene expression in Chinese hamster ovary cells. BMC Biotechnol, 2021
106. A CRISPR-Cas9-Based Near-Infrared Upconversion-Activated DNA Methylation Editing System. ACS Appl Mater Interfaces, 2021
107. Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation. bioRxiv, 2021
108. A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice. Nat Commun, 2021
109. Control of SRC molecular dynamics encodes distinct cytoskeletal responses by specifying signaling pathway usage. J Cell Sci, 2021
110. Optogenetic Control of Phosphatidylinositol (3,4,5)‐triphosphate Production by Light‐sensitive Cryptochrome Proteins on the Plasma Membrane. Chin J Chem, 2021
111. Random sub-diffusion and capture of genes by the nuclear pore reduces dynamics and coordinates interchromosomal movement. bioRxiv, 2021
112. Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. J Biol Chem, 2021
113. Living materials with programmable functionalities grown from engineered microbial co-cultures. Nat Mater, 2021
114. Synthetic gene networks recapitulate dynamic signal decoding and differential gene expression. bioRxiv, 2021
115. A Light-Inducible Split-dCas9 System for Inhibiting the Progression of Bladder Cancer Cells by Activating p53 and E-cadherin. Front Mol Biosci, 2021
116. Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice. Sci Adv, 2021
117. Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse. Proc Natl Acad Sci U S A, 2020
118. Increased lateral tension is sufficient for epithelial folding in Drosophila. Development, 2020
119. Regulating enzymatic reactions in Escherichia coli utilizing light-responsive cellular compartments based on liquid-liquid phase separation. bioRxiv, 2020
120. Spatio-temporal Control of ERK Pulse Frequency Coordinates Fate Decisions during Mammary Acinar Morphogenesis. bioRxiv, 2020
121. Single-Protein Tracking to Study Protein Interactions During Integrin-Based Migration. Methods Mol Biol, 2020
122. Light-inducible Deformation of Mitochondria in Live Cells. bioRxiv, 2020
123. Mechanical competition alters the cellular interpretation of an endogenous genetic programme. bioRxiv, 2020
124. Multichromatic Control of Signaling Pathways in Mammalian Cells. Adv Biosyst, 2020
125. Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila. Elife, 2020
126. Control of Cell Migration Using Optogenetics. Methods Mol Biol, 2020
127. Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast. Cells, 2020
128. CL6mN: Rationally Designed Optogenetic Photoswitches with Tunable Dissociation Dynamics. ACS Synth Biol, 2020
129. A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice. Nat Commun, 2020
130. Photo-SNAP-tag, a Light-Regulated Chemical Labeling System. ACS Chem Biol, 2020
131. Optogenetic Control of Gene Expression Using Cryptochrome 2 and a Light-Activated Degron. Methods Mol Biol, 2020
132. βH-spectrin is required for ratcheting apical pulsatile constrictions during tissue invagination. EMBO Rep, 2020
133. Early But Not Delayed Optogenetic RAF Activation Promotes Astrocytogenesis in Mouse Neural Progenitors. J Mol Biol, 2020
134. Photoactivatable RNA N6 -Methyladenosine Editing with CRISPR-Cas13. Small, 2020
135. Dual Function of PI(4,5)P2 in Insulin-Regulated Exocytic Trafficking of GLUT4 in Adipocytes. J Mol Biol, 2020
136. ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization. Dev Cell, 2020
137. CofActor: A light- and stress-gated optogenetic clustering tool to study disease-associated cytoskeletal dynamics in living cells. J Biol Chem, 2020
138. Optical Activation of TrkB Signaling. J Mol Biol, 2020
139. CLIC4 is a cytokinetic cleavage furrow protein that regulates cortical cytoskeleton stability during cell division. J Cell Sci, 2020
140. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Nat Commun, 2020
141. Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation. Sci Adv, 2020
142. Phosphatidylinositol 4,5-bisphosphate directly interacts with the β and γ subunits of the sodium channel ENaC. J Biol Chem, 2020
143. Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality. Sci Adv, 2020
144. A Generalizable Optogenetic Strategy to Regulate Receptor Tyrosine Kinases during Vertebrate Embryonic Development. J Mol Biol, 2020
145. Cytokinetic bridge triggers de novo lumen formation in vivo. Nat Commun, 2020
146. Tissue-Scale Mechanical Coupling Reduces Morphogenetic Noise to Ensure Precision during Epithelial Folding. Dev Cell, 2020
147. Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds. J Cell Biol, 2020
148. Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation. J Cell Biol, 2020
149. Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling. Nat Commun, 2020
150. Engineering light-controllable CAR T cells for cancer immunotherapy. Sci Adv, 2020
151. Pulsatile MAPK Signaling Modulates p53 Activity to Control Cell Fate Decisions at the G2 Checkpoint for DNA Damage. Cell Rep, 2020
152. Optogenetic control of mRNA localization and translation in live cells. Nat Cell Biol, 2020
153. Cell and tissue manipulation with ultrashort infrared laser pulses in light-sheet microscopy. Sci Rep, 2020
154. Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase. PLoS Biol, 2020
155. Shape-morphing living composites. Sci Adv, 2020
156. Tunable light and drug induced depletion of target proteins. Nat Commun, 2020
157. Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines. Sci Adv, 2020
158. Engineered BRET-Based Biologic Light Sources Enable Spatiotemporal Control over Diverse Optogenetic Systems. ACS Synth Biol, 2019
159. Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Dev Cell, 2019
160. Directed evolution improves the catalytic efficiency of TEV protease. Nat Methods, 2019
161. Blue light-triggered optogenetic system for treating uveal melanoma. Oncogene, 2019
162. A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae. Biotechnol Bioeng, 2019
163. Optogenetic inhibition of Delta reveals digital Notch signaling output during tissue differentiation. EMBO Rep, 2019
164. Imaging of Morphological and Biochemical Hallmarks of Apoptosis with Optimized Optogenetic Actuators. PLoS ONE, 2019
165. Flotillins promote T cell receptor sorting through a fast Rab5-Rab11 endocytic recycling axis. Nat Commun, 2019
166. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat Biotechnol, 2019
167. FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics. Nat Methods, 2019
168. Secretory Vesicle Clustering in Fungal Filamentous Cells Does Not Require Directional Growth. Cell Rep, 2019
169. Light-Induced Transcription Activation for Time-Lapse Microscopy Experiments in Living Cells. Methods Mol Biol, 2019
170. Transient Activations of Rac1 at the Lamellipodium Tip Trigger Membrane Protrusion. Curr Biol, 2019
171. Optogenetic gene editing in regional skin. Cell Res, 2019
172. Achieving tight control of a photoactivatable Cre recombinase gene switch: new design strategies and functional characterization in mammalian cells and rodent. Nucleic Acids Res, 2019
173. Cross-linker-mediated regulation of actin network organization controls tissue morphogenesis. J Cell Biol, 2019
174. LADL: light-activated dynamic looping for endogenous gene expression control. Nat Methods, 2019
175. OpEn-Tag-A Customizable Optogenetic Toolbox To Dissect Subcellular Signaling. ACS Synth Biol, 2019
176. Accurate manipulation of optogenetic proteins with wavelength tunable femtosecond laser system. J Appl Phys, 2019
177. Reversible Optogenetic Control of Growth Factor Signaling During Cell Differentiation and Vertebrate Embryonic Development. OSA Technical Digest, 2019
178. Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos. Cell, 2019
179. Cortical mitochondria regulate insulin secretion by local Ca2+ buffering. J Cell Sci, 2019
180. Advances in optogenetic regulation of gene expression in mammalian cells using cryptochrome 2 (CRY2). Methods, 2019
181. Optogenetic perturbation of the biochemical pathways that control cell behavior. Meth Enzymol, 2019
182. Design, construction, and validation of optogenetic proteins. Lancet Diabetes Endocrinol, 2019
183. Physical Plasma Membrane Perturbation Using Subcellular Optogenetics Drives Integrin-Activated Cell Migration. ACS Synth Biol, 2019
184. Light-Induced Protein Clustering for Optogenetic Interference and Protein Interaction Analysis in Drosophila S2 Cells. Biomolecules, 2019
185. Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem. Biomaterials, 2019
186. A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission. Neuron, 2019
187. Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Nat Commun, 2019
188. Blue Light Switchable Cell–Cell Interactions Provide Reversible and Spatiotemporal Control Towards Bottom-Up Tissue Engineering. Adv Biosyst, 2019
189. Enhanced intrinsic CYP3A4 activity in human hepatic C3A cells with optically controlled CRISPR/dCas9 activator complex. Integr Biol (Camb), 2018
190. Development of a Wireless-Controlled LED Array for the Tunable Optogenetic Control of Cellular Activities. Engineering, 2018
191. Optogenetic dissection of Rac1 and Cdc42 gradient shaping. Nat Commun, 2018
192. Downregulation of basal myosin-II is required for cell shape changes and tissue invagination. EMBO J, 2018
193. Membrane dynamics induced by a PIP3 optogenetic tool. Anal Sci, 2018
194. Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control. Cell, 2018
195. RalB directly triggers invasion downstream Ras by mobilizing the Wave complex. Elife, 2018
196. Light Control of the Tet Gene Expression System in Mammalian Cells. Cell Rep, 2018
197. Optogenetic control of epithelial-mesenchymal transition in cancer cells. Sci Rep, 2018
198. A Single-Component Optogenetic System Allows Stringent Switch of Gene Expression in Yeast Cells. ACS Synth Biol, 2018
199. Spatiotemporal control of zebrafish (Danio rerio) gene expression using a light-activated CRISPR activation system. Gene, 2018
200. Optical activation of TrkA signaling. ACS Synth Biol, 2018
201. Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation. Proc Natl Acad Sci USA, 2018
202. Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis. Nat Commun, 2018
203. Independent Control over Multiple Cell Types in Space and Time Using Orthogonal Blue and Red Light Switchable Cell Interactions. Adv Sci, 2018
204. A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging. Sci Rep, 2018
205. Regulation of cell cycle progression by cell-cell and cell-matrix forces. Nat Cell Biol, 2018
206. Optogenetic inhibition of Gαq protein signaling reduces calcium oscillation stochasticity. ACS Synth Biol, 2018
207. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun, 2018
208. Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation. Sci Rep, 2018
209. A biochemical network controlling basal myosin oscillation. Nat Commun, 2018
210. Optogenetic Control of Cell Migration. Methods Mol Biol, 2018
211. Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci USA, 2018
212. Generation of Optogenetically Modified Adenovirus Vector for Spatiotemporally Controllable Gene Therapy. ACS Chem Biol, 2018
213. Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers. Sci Rep, 2018
214. Spatiotemporal Control of TGF-β Signaling with Light. ACS Synth Biol, 2017
215. Gradients of Rac1 Nanoclusters Support Spatial Patterns of Rac1 Signaling. Cell Rep, 2017
216. Real-time observation of light-controlled transcription in living cells. J Cell Sci, 2017
217. Optogenetic regulation of artificial microRNA improves H2 production in green alga Chlamydomonas reinhardtii. Biotechnol Biofuels, 2017
218. Propagating Wave of ERK Activation Orients Collective Cell Migration. Dev Cell, 2017
219. Near-Infrared Light Triggered Upconversion Optogenetic Nanosystem for Cancer Therapy. ACS Nano, 2017
220. Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase. Cell Chem Biol, 2017
221. Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1. Nucleic Acids Res, 2017
222. A single-chain photoswitchable CRISPR-Cas9 architecture for light-inducible gene editing and transcription. ACS Chem Biol, 2017
223. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017
224. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods, 2017
225. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration. J Biol Chem, 2017
226. Photo-Activatable Akt Probe - A New Tool to Study the Akt-Dependent Physiopathology of Cancer Cells. Oncol Res, 2017
227. An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis. ACS Synth Biol, 2017
228. Vesicle Docking Is a Key Target of Local PI(4,5)P2 Metabolism in the Secretory Pathway of INS-1 Cells. Cell Rep, 2017
229. A calcium- and light-gated switch to induce gene expression in activated neurons. Nat Biotechnol, 2017
230. Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts. Nat Commun, 2017
231. Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development. J Vis Exp, 2017
232. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res, 2017
233. Cell-matrix adhesion and cell-cell adhesion differentially control basal myosin oscillation and Drosophila egg chamber elongation. Nat Commun, 2017
234. Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain. Nat Methods, 2017
235. Light-Regulated Protein Kinases Based on the CRY2-CIB1 System. Methods Mol Biol, 2017
236. Optogenetic control of cellular forces and mechanotransduction. Nat Commun, 2017
237. Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics. Sci Rep, 2017
238. Optogenetic Control of Synaptic Composition and Function. Neuron, 2017
239. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun, 2017
240. A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation. ACS Chem Biol, 2016
241. Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis. Cell Rep, 2016
242. Optogenetic inhibition of apical constriction during Drosophila embryonic development. Methods Cell Biol, 2016
243. An open-hardware platform for optogenetics and photobiology. Sci Rep, 2016
244. A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol, 2016
245. Reversible optogenetic control of kinase activity during differentiation and embryonic development. Development, 2016
246. Optogenetic regulation of site-specific subtelomeric DNA methylation. Oncotarget, 2016
247. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module. Nat Commun, 2016
248. Using HEK293T Expression System to Study Photoactive Plant Cryptochromes. Front Plant Sci, 2016
249. The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress. PLoS ONE, 2016
250. Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action. J Cell Sci, 2016
251. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat Chem Biol, 2016
252. Optogenetic oligomerization of Rab GTPases regulates intracellular membrane trafficking. Nat Chem Biol, 2016
253. Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep, 2016
254. Frequency and amplitude control of cortical oscillations by phosphoinositide waves. Nat Chem Biol, 2016
255. An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis. Dev Cell, 2015
256. Predictive Spatiotemporal Manipulation of Signaling Perturbations Using Optogenetics. Biophys J, 2015
257. Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. ACS Synth Biol, 2015
258. An optogenetic system for interrogating the temporal dynamics of Akt. Sci Rep, 2015
259. Optogenetic Control of Gene Expression in Drosophila. PLoS ONE, 2015
260. Photo-activatable Cre recombinase regulates gene expression in vivo. Sci Rep, 2015
261. Optogenetic apoptosis: light-triggered cell death. Angew Chem Int Ed Engl, 2015
262. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol, 2015
263. The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells. ACS Synth Biol, 2015
264. Optogenetic control of molecular motors and organelle distributions in cells. Chem Biol, 2015
265. A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. Nat Chem Biol, 2015
266. CRISPR-Cas9-based photoactivatable transcription system. Chem Biol, 2015
267. Optogenetic control of organelle transport and positioning. Nature, 2015
268. Single-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signaling. Proc Natl Acad Sci USA, 2015
269. Benchmarking of optical dimerizer systems. ACS Synth Biol, 2014
270. Engineered UV-A light-responsive gene expression system for measuring sun cream efficacy in mammalian cell culture. J Biotechnol, 2014
271. Optogenetic engineering: light-directed cell motility. Angew Chem Int Ed Engl, 2014
272. Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration. Mol Biol Cell, 2014
273. Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling. Nat Commun, 2014
274. Reversible protein inactivation by optogenetic trapping in cells. Nat Methods, 2014
275. Bidirectional regulation of mRNA translation in mammalian cells by using PUF domains. Angew Chem Int Ed Engl, 2014
276. Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth. PLoS ONE, 2014
277. Real-time optogenetic control of intracellular protein concentration in microbial cell cultures. Integr Biol (Camb), 2014
278. Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation. Mol Cell, 2013
279. Light-inducible activation of target mRNA translation in mammalian cells. Chem Commun (Camb), 2013
280. Optical control of mammalian endogenous transcription and epigenetic states. Nature, 2013
281. Optogenetic control of PIP3: PIP3 is sufficient to induce the actin-based active part of growth cones and is regulated via endocytosis. PLoS ONE, 2013
282. Live imaging of multicolor-labeled cells in Drosophila. Development, 2013
283. Optogenetic control of transcription in zebrafish. PLoS ONE, 2012
284. Light-mediated control of DNA transcription in yeast. Methods, 2012
285. Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci USA, 2012
286. Rapid blue-light-mediated induction of protein interactions in living cells. Nat Methods, 2010
287. Quantitative Analysis of Membrane Receptor Trafficking Manipulated by Optogenetic Tools. Methods Mol Biol, 2021
288. Engineered Cas9 extracellular vesicles as a novel gene editing tool. J Extracell Vesicles, 2022
289. Optogenetic Methods to Control Tissue Mechanics in Drosophila. Methods Mol Biol, 2022
290. Optogenetic Control of Membrane Trafficking Using Light-Activated Reversible Inhibition by Assembly Trap of Intracellular Membranes (IM-LARIAT). Methods Mol Biol, 2022