CRY2/CIB1

Related original publications

1. Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos. Cell, 2019
2. Cortical mitochondria regulate insulin secretion by local Ca2+ buffering. J Cell Sci, 2019
3. Advances in optogenetic regulation of gene expression in mammalian cells using cryptochrome 2 (CRY2). Methods, 2019
4. Design, construction, and validation of optogenetic proteins. Lancet Diabetes Endocrinol, 2019
5. Physical Plasma Membrane Perturbation Using Subcellular Optogenetics Drives Integrin-Activated Cell Migration. ACS Synth Biol, 2019
6. Light-Induced Protein Clustering for Optogenetic Interference and Protein Interaction Analysis in Drosophila S2 Cells. Biomolecules, 2019
7. Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem. Biomaterials, 2019
8. Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Nat Commun, 2019
9. Blue Light Switchable Cell–Cell Interactions Provide Reversible and Spatiotemporal Control Towards Bottom-Up Tissue Engineering. Adv Biosyst, 2019
10. Enhanced intrinsic CYP3A4 activity in human hepatic C3A cells with optically controlled CRISPR/dCas9 activator complex. Integr Biol (Camb), 2018
11. Development of a Wireless-Controlled LED Array for the Tunable Optogenetic Control of Cellular Activities. Engineering, 2018
12. Optogenetic dissection of Rac1 and Cdc42 gradient shaping. Nat Commun, 2018
13. Downregulation of basal myosin-II is required for cell shape changes and tissue invagination. EMBO J, 2018
14. Membrane dynamics induced by a PIP3 optogenetic tool. Anal Sci, 2018
15. Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control. Cell, 2018
16. RalB directly triggers invasion downstream Ras by mobilizing the Wave complex. Elife, 2018
17. Light Control of the Tet Gene Expression System in Mammalian Cells. Cell Rep, 2018
18. Optogenetic control of epithelial-mesenchymal transition in cancer cells. Sci Rep, 2018
19. A Single-Component Optogenetic System Allows Stringent Switch of Gene Expression in Yeast Cells. ACS Synth Biol, 2018
20. Spatiotemporal control of zebrafish (Danio rerio) gene expression using a light-activated CRISPR activation system. Gene, 2018
21. Optical activation of TrkA signaling. ACS Synth Biol, 2018
22. Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation. Proc Natl Acad Sci USA, 2018
23. Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis. Nat Commun, 2018
24. LADL: Light-activated dynamic looping for endogenous gene expression control. bioRxiv, 2018
25. Independent Control over Multiple Cell Types in Space and Time Using Orthogonal Blue and Red Light Switchable Cell Interactions. Adv Sci, 2018
26. A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging. Sci Rep, 2018
27. Regulation of cell cycle progression by cell-cell and cell-matrix forces. Nat Cell Biol, 2018
28. Optogenetic inhibition of Gαq protein signaling reduces calcium oscillation stochasticity. ACS Synth Biol, 2018
29. Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation. Sci Rep, 2018
30. A biochemical network controlling basal myosin oscillation. Nat Commun, 2018
31. Optogenetic Control of Cell Migration. Methods Mol Biol, 2018
32. Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci USA, 2018
33. Generation of Optogenetically Modified Adenovirus Vector for Spatiotemporally Controllable Gene Therapy. ACS Chem Biol, 2018
34. Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers. Sci Rep, 2018
35. Spatiotemporal Control of TGF-β Signaling with Light. ACS Synth Biol, 2017
36. Gradients of Rac1 Nanoclusters Support Spatial Patterns of Rac1 Signaling. Cell Rep, 2017
37. Real-time observation of light-controlled transcription in living cells. J Cell Sci, 2017
38. Optogenetic regulation of artificial microRNA improves H2 production in green alga Chlamydomonas reinhardtii. Biotechnol Biofuels, 2017
39. Propagating Wave of ERK Activation Orients Collective Cell Migration. Dev Cell, 2017
40. Near-Infrared Light Triggered Upconversion Optogenetic Nanosystem for Cancer Therapy. ACS Nano, 2017
41. Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase. Cell Chem Biol, 2017
42. Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1. Nucleic Acids Res, 2017
43. A single-chain photoswitchable CRISPR-Cas9 architecture for light-inducible gene editing and transcription. ACS Chem Biol, 2017
44. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017
45. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods, 2017
46. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration. J Biol Chem, 2017
47. Photo-Activatable Akt Probe - A New Tool to Study the Akt-Dependent Physiopathology of Cancer Cells. Oncol Res, 2017
48. An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis. ACS Synth Biol, 2017
49. Vesicle Docking Is a Key Target of Local PI(4,5)P2 Metabolism in the Secretory Pathway of INS-1 Cells. Cell Rep, 2017
50. A calcium- and light-gated switch to induce gene expression in activated neurons. Nat Biotechnol, 2017
51. Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts. Nat Commun, 2017
52. Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development. J Vis Exp, 2017
53. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res, 2017
54. Cell-matrix adhesion and cell-cell adhesion differentially control basal myosin oscillation and Drosophila egg chamber elongation. Nat Commun, 2017
55. Light-Regulated Protein Kinases Based on the CRY2-CIB1 System. Methods Mol Biol, 2017
56. Optogenetic control of cellular forces and mechanotransduction. Nat Commun, 2017
57. Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics. Sci Rep, 2017
58. Optogenetic Control of Synaptic Composition and Function. Neuron, 2017
59. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun, 2017
60. A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation. ACS Chem Biol, 2016
61. Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis. Cell Rep, 2016
62. Optogenetic inhibition of apical constriction during Drosophila embryonic development. Methods Cell Biol, 2016
63. An open-hardware platform for optogenetics and photobiology. Sci Rep, 2016
64. A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol, 2016
65. Reversible optogenetic control of kinase activity during differentiation and embryonic development. Development, 2016
66. Optogenetic regulation of site-specific subtelomeric DNA methylation. Oncotarget, 2016
67. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module. Nat Commun, 2016
68. Using HEK293T Expression System to Study Photoactive Plant Cryptochromes. Front Plant Sci, 2016
69. The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress. PLoS ONE, 2016
70. Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action. J Cell Sci, 2016
71. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat Chem Biol, 2016
72. Optogenetic oligomerization of Rab GTPases regulates intracellular membrane trafficking. Nat Chem Biol, 2016
73. Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep, 2016
74. Frequency and amplitude control of cortical oscillations by phosphoinositide waves. Nat Chem Biol, 2016
75. An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis. Dev Cell, 2015
76. Predictive Spatiotemporal Manipulation of Signaling Perturbations Using Optogenetics. Biophys J, 2015
77. Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. ACS Synth Biol, 2015
78. An optogenetic system for interrogating the temporal dynamics of Akt. Sci Rep, 2015
79. Optogenetic Control of Gene Expression in Drosophila. PLoS ONE, 2015
80. Photo-activatable Cre recombinase regulates gene expression in vivo. Sci Rep, 2015
81. Optogenetic apoptosis: light-triggered cell death. Angew Chem Int Ed Engl, 2015
82. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol, 2015
83. The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells. ACS Synth Biol, 2015
84. Optogenetic control of molecular motors and organelle distributions in cells. Chem Biol, 2015
85. A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. Nat Chem Biol, 2015
86. CRISPR-Cas9-based photoactivatable transcription system. Chem Biol, 2015
87. Optogenetic control of organelle transport and positioning. Nature, 2015
88. Single-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signaling. Proc Natl Acad Sci USA, 2015
89. Benchmarking of optical dimerizer systems. ACS Synth Biol, 2014
90. Engineered UV-A light-responsive gene expression system for measuring sun cream efficacy in mammalian cell culture. J Biotechnol, 2014
91. Optogenetic engineering: light-directed cell motility. Angew Chem Int Ed Engl, 2014
92. Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration. Mol Biol Cell, 2014
93. Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling. Nat Commun, 2014
94. Reversible protein inactivation by optogenetic trapping in cells. Nat Methods, 2014
95. Bidirectional regulation of mRNA translation in mammalian cells by using PUF domains. Angew Chem Int Ed Engl, 2014
96. Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth. PLoS ONE, 2014
97. Real-time optogenetic control of intracellular protein concentration in microbial cell cultures. Integr Biol (Camb), 2014
98. Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation. Mol Cell, 2013
99. Light-inducible activation of target mRNA translation in mammalian cells. Chem Commun (Camb), 2013
100. Optical control of mammalian endogenous transcription and epigenetic states. Nature, 2013
101. Optogenetic control of PIP3: PIP3 is sufficient to induce the actin-based active part of growth cones and is regulated via endocytosis. PLoS ONE, 2013
102. Live imaging of multicolor-labeled cells in Drosophila. Development, 2013
103. Optogenetic control of transcription in zebrafish. PLoS ONE, 2012
104. Light-mediated control of DNA transcription in yeast. Methods, 2012
105. Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci USA, 2012
106. Rapid blue-light-mediated induction of protein interactions in living cells. Nat Methods, 2010