News and Updates

Oct. 04, 2023 | Research Highlights in September
Aug. 06, 2023 | Research Highlights in July

Fascinating research in combination with a little bit of fun:

Paper of the Month July: "A biological camera that captures and stores images directly into DNA."

Featured Paper: "Designer Condensates: A Toolkit for the Biomolecular Architect."

June 04, 2023 | Research Highlights in May:
May 05, 2023 | Research Highlights in April

Paper of the Month April: A light-inactivated degron: Controlling protein stability with SULI, a highly sensitive tag for stabilization upon light induction.

Featured Papers: Learn more about light-activated degrons for mammalian cells and yeast.

April 03, 2023 | Research Highlights in March
March 04, 2023 | Research Highlights in February
Jan. 02, 2023 | Research Highlights in December

Paper of the Month December: Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles.

Featured Paper: Learn more about optogenetic inactivation of proteins with the "LARIAT" tool. 

Dec. 04, 2022 | Research Highlights in November

Paper of the Month November:  Patterned mechanical feedback establishes a global myosin gradient.

Featured Paper: First published application of an optogentic switch in Drosophila: Fast manipulation of cellular cAMP level by light in vivo.

Nov. 04, 2022 | Research Highlights in October
Oct. 04, 2022 | Research Highlights in September
Oct. 02, 2022 | The Optogenetics Conference 2022 | Learn more at their website:


Sept. 04, 2022 | Research Highlights in August
Aug. 04, 2022 | Research Highlights in July

Paper of the Month July: A new sophisticated illumination device called "LITOS".  Check out other illumination devices in our Materials section.

Featured Paper: Learn more about Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.

July 04, 2022 | Research Highlights in June

Paper of the Month June: Development of the MagRed (DrBphP/Aff6_V18FΔN) switch: A red light-responsive photoswitch for deep tissue optogenetics.

Featured Paper: First application of the DrBphP switch: Neurotrophin receptor tyrosine kinases regulated with near-infrared light.

May 06, 2022 | Research Highlights in April

Using bioluminescence to activate optogenetic switches and for communication between cells: 

Paper of the Month April: Synthetic cells with self-activating optogenetic proteins communicate with natural cells.

Featured Paper: Cell to Cell Signaling through Light in Artificial Cell Communities: Glowing Predator Lures Prey.

April 08, 2022 | Research Highlights in March
Feb. 10, 2022 | New tag: Extracellular optogenetics

We constantly adapt optoBase for the latest molecular optogenetic trends. Thus, the new application tag Extracellular optogenetics includes all publications in our database that

  • apply photoreceptors in vitro beyond characterization studies and
  • systems where photoreceptors are expressed on the outer cell surface.

We hope that this new tag streamlines your search on optoBase and welcome suggestions for future tags. Your optoBase-team

Feb. 10, 2022 | Featured Extracellular Optogenetics Publication
Dec. 04, 2021 | Research Highlights in November
Nov. 04, 2021 | Research Highlights in October

Paper of the Month October: A light tunable differentiation system for the creation and control of consortia in yeast.

Featured Paper: Learn more about optogenetics in yeast: The rise and shine of yeast optogenetics.

Oct. 05, 2021 | Research Highlights in September
Sept. 06, 2021 | Research Highlights in August

Paper of the month August: A guide to the optogenetic regulation of endogenous molecules.

Featured Paper: Learn more about RNA editing with the photoactivatable CRISPR-Cas13: Photoactivatable RNA N6-Methyladenosine Editing with CRISPR-Cas13.

Aug. 04, 2021 | Review Highlights in July
July 04, 2021 | Research Highlights in June
June 04, 2021 | Research Highlights in May

Paper of the month May: Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering.

Featured Paper: Learn more about optogenetic tools based on LOV domains: LOVTRAP: an optogenetic system for photoinduced protein dissociation.

May 04, 2021 | Research Highlights in April
April 04, 2021 | Research Highlights in March

Paper of the month March: For a broad overview over the field of Molecular Optogenetics: Steering Molecular Activity with Optogenetics: Recent Advances and Perspectives.

Featured Paper: Optogenetics sheds new light on tissue engineering and regenerative medicine.

April 03, 2021 | The Optogenetics Conference 2021 | Learn more at their website:


March 04, 2021 | Research Highlights in February
Feb. 04, 2021 | Research Highlights in January
Jan. 04, 2021 | The OptoBase-Team wishes everyone a happy and healthy new year!

Research Highlights in December

Dec. 04, 2020 | Research Highlights in November
Nov. 04, 2020 | Research Highlights in October
Oct. 04, 2020 | Research Highlights in September
Sept. 04, 2020 | Research Highlights in August
July 07, 2020 | New Regularly Updated Feature on OptoBase

We are happy to introduce the “Paper of the Month”, which highlights one outstanding research paper of the previous month. Furthermore, the OptoBase team chooses one additional, groundbreaking paper from our extensive, weekly updated database.

Aug. 06, 2019 | Search for Publications by Journal

Use the new OptoBase syntax option — journal:”name of your journal of interest” — to search for papers by journal name, be it a full name or its ISO abbreviation. Extra tip: use partial queries, such as journal:"ACS" or journal:”Nature”, to retrieve papers from whole journal collections. 

Jan. 13, 2019 | New year, new tool: Glossary

OptoBase has been upgraded with a new tool — Glossary. There you will find brief definitions of various terms and abbreviations commonly used in optogenetics. P.s.: You are most welcome to suggest new terms via our submission form

June 25, 2018 | How to cite OptoBase

We are proud to announce that the paper presenting OptoBase got last week successfully published in ACS Synthetic Biology. If you refer to OptoBase in your work, please cite it as this publication!

May 16, 2018 | How to get the most out of your search?

Improve your publication search experience by getting to know our database and learning about the OptoBase-specific syntax, now further explained with a set of helpful examples.

Feb. 21, 2018 | Find The Application

Looking for optogenetic publications presenting a particular type of biological application(s)? The new tool, Find The Application, helps you find them instantly.

July 17, 2017 | Frequently Asked Questions

A FAQ section was added to improve the OptoBase usability.

June 19, 2017 | Find The Switch

Check out our new tool that helps you find the most suitable optogenetic switches for your upcoming project.  

May 10, 2017 | New Switches

The set of switches with a predefined function was added to complete our collection of optogenetic switches.

April 09, 2017 | Welcome to OptoBase

Launch Version 1.0