Photoreceptor PYP
Binding partner /
Cofactor p-coumaric acid
Source organism Halorhodospira halophila
Mode of action intramolecular conformational change
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time seconds
Crystal structure of PYP, ground state. (PDB ID: 5HD3)

Related original publications

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  1. A yeast system for discovering optogenetic inhibitors of eukaryotic translation initiation. ACS Synth Biol, 2019
  2. Discovering selective binders for photoswitchable proteins using phage display. ACS Synth Biol, 2018
  3. Optogenetic Inhibitor of the Transcription Factor CREB. Chem Biol, 2015
  4. A photoswitchable DNA-binding protein based on a truncated GCN4-photoactive yellow protein chimera. Photochem Photobiol Sci, 2010