bPAC (BlaC)

Related original publications

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3. An Integrated Optogenetic and Bioelectronic Platform for Regulating Cardiomyocyte Function. Adv Sci (Weinh), 2024
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6. Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length. J Cell Biol, 2024
7. Optogenetic induction of chronic glucocorticoid exposure in early-life leads to blunted stress-response in larval zebrafish. Eur J Neurosci, 2024
8. Live-cell fluorescence imaging and optogenetic control of PKA kinase activity in fission yeast Schizosaccharomyces pombe. Yeast, 2024
9. Light-Mediated Enhancement of Glucose-Stimulated Insulin Release of Optogenetically Engineered Human Pancreatic Beta-Cells. ACS Synth Biol, 2024
10. Mapping the Cellular Distribution of an Optogenetic Protein Using a Light-Stimulation Grid Mapping the Cellular Distribution of an Optogenetic Protein Using a Light-Stimulation Grid. J Vis Exp, 2024
11. Live-cell fluorescence imaging and optogenetic control of PKA kinase activity in fission yeast Schizosaccharomyces pombe. bioRxiv, 2024
12. Lifelong molecular consequences of high Glucocorticoids exposure during development bioRxiv, 2024
13. Pathogen infection induces sickness behaviors by recruiting neuromodulatory systems linked to stress and satiety in C. elegans. bioRxiv, 2024
14. Optogenetic demonstration of the involvement of SMA-negative mural cells in the regulation of cerebral blood flow. Front Physiol, 2023
15. Rab3 mediates cyclic AMP-dependent presynaptic plasticity and olfactory learning. bioRxiv, 2023
16. Optogenetic manipulation of neuronal and cardiomyocyte functions in zebrafish using microbial rhodopsins and adenylyl cyclases. Elife, 2023
17. All-optical mapping of cAMP transport reveals rules of sub-cellular localization. bioRxiv, 2023
18. Soluble cyclase-mediated nuclear cAMP synthesis is sufficient for cell proliferation. Proc Natl Acad Sci U S A, 2023
19. Optogenetic Stimulation Array for Confocal Microscopy Fast Transient Monitoring. TBioCAS, 2022
20. Photoactivated adenylyl cyclases attenuate sepsis-induced cardiomyopathy by suppressing macrophage-mediated inflammation. Front Immunol, 2022
21. GPCR-dependent spatiotemporal cAMP generation confers functional specificity in cardiomyocytes and cardiac responses. bioRxiv, 2022
22. A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation. EMBO Rep, 2022
23. Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling. Nature, 2021
24. Endosomal cAMP production broadly impacts the cellular phosphoproteome. J Biol Chem, 2021
25. mem-iLID, a fast and economic protein purification method. Biosci Rep, 2021
26. Vertebrate cells differentially interpret ciliary and extraciliary cAMP. Cell, 2021
27. Optogenetic tools for manipulation of cyclic nucleotides, functionally coupled to CNG-channels. Br J Pharmacol, 2021
28. Optogenetic modulation of real-time nanoscale dynamics of HCN channels using photoactivated adenylyl cyclases. RSC Chem Biol, 2021
29. Light-Induced Change of Arginine Conformation Modulates the Rate of Adenosine Triphosphate to Cyclic Adenosine Monophosphate Conversion in the Optogenetic System Containing Photoactivated Adenylyl Cyclase. J Chem Inf Model, 2021
30. Optogenetic Modification of Pseudomonas aeruginosa Enables Controllable Twitching Motility and Host Infection. ACS Synth Biol, 2021
31. Biphasic Response of Protein Kinase A to Cyclic Adenosine Monophosphate Triggers Distinct Epithelial Phenotypes. bioRxiv, 2020
32. SynaptoPAC, an optogenetic tool for induction of presynaptic plasticity. J Neurochem, 2020
33. Dual Activation of cAMP Production Through Photostimulation or Chemical Stimulation. Methods Mol Biol, 2020
34. Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium. Elife, 2020
35. Optogenetic Manipulation of Postsynaptic cAMP Using a Novel Transgenic Mouse Line Enables Synaptic Plasticity and Enhances Depolarization Following Tetanic Stimulation in the Hippocampal Dentate Gyrus. Front Neural Circuits, 2020
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37. An optogenetic tool for induced protein stabilization based on the Phaeodactylum tricornutum aureochrome 1a LOV domain. J Mol Biol, 2020
38. Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Dev Cell, 2019
39. Amelioration of Diabetes in a Murine Model upon Transplantation of Pancreatic β-Cells with Optogenetic Control of Cyclic Adenosine Monophosphate. ACS Synth Biol, 2019
40. Compartmentalized cAMP Generation by Engineered Photoactivated Adenylyl Cyclases. Cell Chem Biol, 2019
41. Using a Robust and Sensitive GFP-Based cGMP Sensor for Real Time Imaging in Intact Caenorhabditis elegans. Genetics, 2019
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44. Potassium channel-based optogenetic silencing. Nat Commun, 2018
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47. Optogenetic regulation of insulin secretion in pancreatic β-cells. Sci Rep, 2017
48. Red fluorescent protein-based cAMP indicator applicable to optogenetics and in vivo imaging. Sci Rep, 2017
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50. Model-guided optogenetic study of PKA signaling in budding yeast. Mol Biol Cell, 2016
51. Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium. Proc Natl Acad Sci USA, 2016
52. The rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling. Sci Signal, 2015
53. Manipulation of Interrenal Cell Function in Developing Zebrafish Using Genetically Targeted Ablation and an Optogenetic Tool. Endocrinology, 2015
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57. Natural and engineered photoactivated nucleotidyl cyclases for optogenetic applications. J Biol Chem, 2010
58. Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa. J Biol Chem, 2010