CRY2/CIB1

Related original publications

1. Optogenetic control of Protein Kinase C-epsilon activity reveals its intrinsic signaling properties with spatiotemporal resolution. bioRxiv, 2025
2. Precise Control of Intracellular Trafficking and Receptor-Mediated Endocytosis in Living Cells and Behaving Animals. Adv Sci (Weinh), 2024
3. Optogenetic Control of the Mitochondrial Protein Import in Mammalian Cells. Cells, 2024
4. Precision in situ cryo-correlative light and electron microscopy of optogenetically-positioned organelles. J Cell Sci, 2024
5. Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2. Proc Natl Acad Sci U S A, 2024
6. PIP5K-Ras bistability initiates plasma membrane symmetry breaking to regulate cell polarity and migration. bioRxiv, 2024
7. Selective optogenetic inhibition of Gαq or Gαi signaling by minimal RGS domains disrupts circuit functionality and circuit formation. Proc Natl Acad Sci U S A, 2024
8. Optogenetic Strategies for Optimizing the Performance of Phospholipids Biosensors. Adv Sci (Weinh), 2024
9. Exploring plant-derived phytochrome chaperone proteins for light-switchable transcriptional regulation in mammals. Nat Commun, 2024
10. AGS3-based optogenetic GDI induces GPCR-independent Gβγ signaling and macrophage migration. bioRxiv, 2024
11. Spatiotemporal Control of Inflammatory Lytic Cell Death Through Optogenetic Induction of RIPK3 Oligomerization. J Mol Biol, 2024
12. Dynamic Multiplexed Control and Modeling of Optogenetic Systems Using the High-Throughput Optogenetic Platform, Lustro. ACS Synth Biol, 2024
13. Optogenetic control of Nodal signaling patterns. bioRxiv, 2024
14. Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice. Small, 2024
15. Temporal dynamics of BMP/Nodal ratio drive tissue-specific gastrulation morphogenesis. bioRxiv, 2024
16. Enhancing high-throughput optogenetics: Integration of LITOS with Lustro enables simultaneous light stimulation and shaking. MicroPubl Biol, 2024
17. Ultralow Background Membrane Editors for Spatiotemporal Control of Phosphatidic Acid Metabolism and Signaling ACS Cent Sci, 2024
18. Development of an optogenetics tool, Opto-RANK, for control of osteoclast differentiation using blue light. Sci Rep, 2024
19. A mechanical wave travels along a genetic guide to drive the formation of an epithelial furrow during Drosophila gastrulation. Dev Cell, 2024
20. A platform to induce and mature biomolecular condensates using chemicals and light. Nat Chem Biol, 2024
21. Engineered poly(A)-surrogates for translational regulation and therapeutic biocomputation in mammalian cells. Cell Res, 2024
22. Bidirectional Allosteric Coupling between PIP2 Binding and the Pore of the Oncochannel TRPV6. Int J Mol Sci, 2024
23. Optogenetic induction of caspase-8 mediated apoptosis by employing Arabidopsis cryptochrome 2. Sci Rep, 2023
24. Spatiotemporal Optical Control of Gαq-PLCβ Interactions. ACS Synth Biol, 2023
25. A single-component, light-assisted uncaging switch for endoproteolytic release. Nat Chem Biol, 2023
26. A programmable protease-based protein secretion platform for therapeutic applications. Nat Chem Biol, 2023
27. AAV-compatible optogenetic tools for activating endogenous calcium channels in vivo. Mol Brain, 2023
28. Spatiotemporal, optogenetic control of gene expression in organoids. Nat Methods, 2023
29. Photoactivatable base editors for spatiotemporally controlled genome editing in vivo. Biomaterials, 2023
30. Diya – a universal light illumination platform for multiwell plate cultures. iScience, 2023
31. Cell Cycle Control by Optogenetically Regulated Cell Cycle Inhibitor Protein p21. Biology (Basel), 2023
32. Force propagation between epithelial cells depends on active coupling and mechano-structural polarization. Elife, 2023
33. High-Throughput Optogenetics Experiments in Yeast Using the Automated Platform Lustro. J Vis Exp, 2023
34. Automatic detection of spatio-temporal signalling patterns in cell collectives. J Cell Biol, 2023
35. Tissue Flows Are Tuned by Actomyosin-Dependent Mechanics in Developing Embryos. PRX Life, 2023
36. Optogenetic control of Cdc48 for dynamic metabolic engineering in yeast. Metab Eng, 2023
37. Concept and considerations of a medical device: the active noise cancelling incubator. Front Pediatr, 2023
38. An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells. Nat Commun, 2023
39. Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair. J Nanobiotechnology, 2023
40. Activity-based directed evolution of a membrane editor in mammalian cells. Nat Chem, 2023
41. Actuation of single downstream nodes in growth factor network steers immune cell migration. Dev Cell, 2023
42. Rab8, Rab11, and Rab35 coordinate lumen and cilia formation during zebrafish left-right organizer development. PLoS Genet, 2023
43. OptIC Notch reveals mechanism that regulates receptor interactions with CSL. Development, 2023
44. Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling. Cell Rep, 2023
45. Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation. bioRxiv, 2023
46. Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos. J Vis Exp, 2023
47. Optogenetic decoding of Akt2-regulated metabolic signaling pathways in skeletal muscle cells using transomics analysis. Sci Signal, 2023
48. Light-driven biological actuators to probe the rheology of 3D microtissues. Nat Commun, 2023
49. Polarized branched Actin modulates cortical mechanics to produce unequal-size daughters during asymmetric division. Nat Cell Biol, 2023
50. Cell size and actin architecture determine force generation in optogenetically activated cells. Biophys J, 2023
51. An optogenetic tool to inhibit RhoA in Drosophila embryos. STAR Protoc, 2023
52. Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles. Nat Commun, 2022
53. An Optogenetic-Controlled Cell Reprogramming System for Driving Cell Fate and Light-Responsive Chimeric Mice. Adv Sci (Weinh), 2022
54. Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis. Proc Natl Acad Sci U S A, 2022
55. Patterned mechanical feedback establishes a global myosin gradient. Nat Commun, 2022
56. Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation. Cell Chem Biol, 2022
57. Stable Transgenic Mouse Strain with Enhanced Photoactivatable Cre Recombinase for Spatiotemporal Genome Manipulation. Adv Sci (Weinh), 2022
58. Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration. Nat Cell Biol, 2022
59. Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis. Dev Cell, 2022
60. Optogenetic manipulation of cell migration with high spatiotemporal resolution using lattice lightsheet microscopy. Commun Biol, 2022
61. LITOS: a versatile LED illumination tool for optogenetic stimulation. Sci Rep, 2022
62. Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts. Nat Commun, 2022
63. Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude. Cell Rep, 2022
64. Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion. Nat Commun, 2022
65. Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms. Proc Natl Acad Sci U S A, 2022
66. Precise control of microtubule disassembly in living cells. EMBO J, 2022
67. Transcription activation is enhanced by multivalent interactions independent of phase separation. Mol Cell, 2022
68. Light-induced fermenter production of derivatives of the sweet protein monellin is maximized in prestationary Saccharomyces cerevisiae cultures. Biotechnol J, 2022
69. Cell division in tissues enables macrophage infiltration. Science, 2022
70. Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition. J Cell Sci, 2022
71. An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins. J Biol Chem, 2022
72. Optogenetic Control of PIP2 Interactions Shaping ENaC Activity. Int J Mol Sci, 2022
73. Synthetic gene networks recapitulate dynamic signal decoding and differential gene expression. Cell Syst, 2022
74. Optogenetic inhibition of actomyosin reveals mechanical bistability of the mesoderm epithelium during Drosophila mesoderm invagination. Elife, 2022
75. Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins. Nat Biotechnol, 2022
76. CeLINC, a fluorescence-based protein-protein interaction assay in Caenorhabditis elegans. Genetics, 2021
77. Optogenetic relaxation of actomyosin contractility uncovers mechanistic roles of cortical tension during cytokinesis. Nat Commun, 2021
78. Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety. Nat Nanotechnol, 2021
79. Cell patterning by secretion-induced plasma membrane flows. Sci Adv, 2021
80. An active tethering mechanism controls the fate of vesicles. Nat Commun, 2021
81. Revisiting the Role of TGFβ Receptor Internalization for Smad Signaling: It is Not Required in Optogenetic TGFβ Signaling Systems. Adv Biol (Weinh), 2021
82. Mechanical competition alters the cellular interpretation of an endogenous genetic programme. J Cell Biol, 2021
83. Optogenetic Tools for Control of Public Goods in Saccharomyces cerevisiae. mSphere, 2021
84. Mapping the dynamic transfer functions of eukaryotic gene regulation. Cell Syst, 2021
85. Using optogenetics to link myosin patterns to contractile cell behaviors during convergent extension. Biophys J, 2021
86. Light-inducible deformation of mitochondria in live cells. Cell Chem Biol, 2021
87. Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival. Dev Cell, 2021
88. Exosome-based delivery of super-repressor IκBα ameliorates kidney ischemia-reperfusion injury. Kidney Int, 2021
89. Optogenetic Control of the Canonical Wnt Signaling Pathway During Xenopus laevis Embryonic Development. J Mol Biol, 2021
90. Random sub-diffusion and capture of genes by the nuclear pore reduces dynamics and coordinates inter-chromosomal movement. Elife, 2021
91. PIP2 regulation of TRPC5 channel activation and desensitization. J Biol Chem, 2021
92. Optogenetic-based Localization of Talin to the Plasma Membrane Promotes Activation of β3 Integrins. J Biol Chem, 2021
93. A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch. Elife, 2021
94. CRISPR-dcas9 Optogenetic Nanosystem for the Blue Light-Mediated Treatment of Neovascular Lesions. ACS Appl Bio Mater, 2021
95. Transient light-activated gene expression in Chinese hamster ovary cells. BMC Biotechnol, 2021
96. A CRISPR-Cas9-Based Near-Infrared Upconversion-Activated DNA Methylation Editing System. ACS Appl Mater Interfaces, 2021
97. A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice. Nat Commun, 2021
98. Control of SRC molecular dynamics encodes distinct cytoskeletal responses by specifying signaling pathway usage. J Cell Sci, 2021
99. Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. J Biol Chem, 2021
100. Living materials with programmable functionalities grown from engineered microbial co-cultures. Nat Mater, 2021
101. A Light-Inducible Split-dCas9 System for Inhibiting the Progression of Bladder Cancer Cells by Activating p53 and E-cadherin. Front Mol Biosci, 2021
102. Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice. Sci Adv, 2021
103. Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse. Proc Natl Acad Sci U S A, 2020
104. Increased lateral tension is sufficient for epithelial folding in Drosophila. Development, 2020
105. Single-Protein Tracking to Study Protein Interactions During Integrin-Based Migration. Methods Mol Biol, 2020
106. Multichromatic Control of Signaling Pathways in Mammalian Cells. Adv Biosyst, 2020
107. Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila. Elife, 2020
108. Control of Cell Migration Using Optogenetics. Methods Mol Biol, 2020
109. Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast. Cells, 2020
110. CL6mN: Rationally Designed Optogenetic Photoswitches with Tunable Dissociation Dynamics. ACS Synth Biol, 2020
111. A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice. Nat Commun, 2020
112. Photo-SNAP-tag, a Light-Regulated Chemical Labeling System. ACS Chem Biol, 2020
113. Optogenetic Control of Gene Expression Using Cryptochrome 2 and a Light-Activated Degron. Methods Mol Biol, 2020
114. βH-spectrin is required for ratcheting apical pulsatile constrictions during tissue invagination. EMBO Rep, 2020
115. Early But Not Delayed Optogenetic RAF Activation Promotes Astrocytogenesis in Mouse Neural Progenitors. J Mol Biol, 2020
116. Photoactivatable RNA N6 -Methyladenosine Editing with CRISPR-Cas13. Small, 2020
117. Dual Function of PI(4,5)P2 in Insulin-Regulated Exocytic Trafficking of GLUT4 in Adipocytes. J Mol Biol, 2020
118. ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization. Dev Cell, 2020
119. CofActor: A light- and stress-gated optogenetic clustering tool to study disease-associated cytoskeletal dynamics in living cells. J Biol Chem, 2020
120. Optical Activation of TrkB Signaling. J Mol Biol, 2020
121. CLIC4 is a cytokinetic cleavage furrow protein that regulates cortical cytoskeleton stability during cell division. J Cell Sci, 2020
122. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Nat Commun, 2020
123. Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation. Sci Adv, 2020
124. Phosphatidylinositol 4,5-bisphosphate directly interacts with the β and γ subunits of the sodium channel ENaC. J Biol Chem, 2020
125. Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality. Sci Adv, 2020
126. A Generalizable Optogenetic Strategy to Regulate Receptor Tyrosine Kinases during Vertebrate Embryonic Development. J Mol Biol, 2020
127. Cytokinetic bridge triggers de novo lumen formation in vivo. Nat Commun, 2020
128. Tissue-Scale Mechanical Coupling Reduces Morphogenetic Noise to Ensure Precision during Epithelial Folding. Dev Cell, 2020
129. Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds. J Cell Biol, 2020
130. Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation. J Cell Biol, 2020
131. Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling. Nat Commun, 2020
132. Engineering light-controllable CAR T cells for cancer immunotherapy. Sci Adv, 2020
133. Pulsatile MAPK Signaling Modulates p53 Activity to Control Cell Fate Decisions at the G2 Checkpoint for DNA Damage. Cell Rep, 2020
134. Optogenetic control of mRNA localization and translation in live cells. Nat Cell Biol, 2020
135. Cell and tissue manipulation with ultrashort infrared laser pulses in light-sheet microscopy. Sci Rep, 2020
136. Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase. PLoS Biol, 2020
137. Shape-morphing living composites. Sci Adv, 2020
138. Tunable light and drug induced depletion of target proteins. Nat Commun, 2020
139. Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines. Sci Adv, 2020
140. Engineered BRET-Based Biologic Light Sources Enable Spatiotemporal Control over Diverse Optogenetic Systems. ACS Synth Biol, 2019
141. Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Dev Cell, 2019
142. Directed evolution improves the catalytic efficiency of TEV protease. Nat Methods, 2019
143. Blue light-triggered optogenetic system for treating uveal melanoma. Oncogene, 2019
144. A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae. Biotechnol Bioeng, 2019
145. Optogenetic inhibition of Delta reveals digital Notch signaling output during tissue differentiation. EMBO Rep, 2019
146. Imaging of Morphological and Biochemical Hallmarks of Apoptosis with Optimized Optogenetic Actuators. PLoS ONE, 2019
147. Flotillins promote T cell receptor sorting through a fast Rab5-Rab11 endocytic recycling axis. Nat Commun, 2019
148. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat Biotechnol, 2019
149. FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics. Nat Methods, 2019
150. Secretory Vesicle Clustering in Fungal Filamentous Cells Does Not Require Directional Growth. Cell Rep, 2019
151. Light-Induced Transcription Activation for Time-Lapse Microscopy Experiments in Living Cells. Methods Mol Biol, 2019
152. Transient Activations of Rac1 at the Lamellipodium Tip Trigger Membrane Protrusion. Curr Biol, 2019
153. Optogenetic gene editing in regional skin. Cell Res, 2019
154. Achieving tight control of a photoactivatable Cre recombinase gene switch: new design strategies and functional characterization in mammalian cells and rodent. Nucleic Acids Res, 2019
155. Cross-linker-mediated regulation of actin network organization controls tissue morphogenesis. J Cell Biol, 2019
156. LADL: light-activated dynamic looping for endogenous gene expression control. Nat Methods, 2019
157. OpEn-Tag-A Customizable Optogenetic Toolbox To Dissect Subcellular Signaling. ACS Synth Biol, 2019
158. Accurate manipulation of optogenetic proteins with wavelength tunable femtosecond laser system. J Appl Phys, 2019
159. Reversible Optogenetic Control of Growth Factor Signaling During Cell Differentiation and Vertebrate Embryonic Development. OSA Technical Digest, 2019
160. Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos. Cell, 2019
161. Cortical mitochondria regulate insulin secretion by local Ca2+ buffering. J Cell Sci, 2019
162. Advances in optogenetic regulation of gene expression in mammalian cells using cryptochrome 2 (CRY2). Methods, 2019
163. Optogenetic perturbation of the biochemical pathways that control cell behavior. Meth Enzymol, 2019
164. Design, construction, and validation of optogenetic proteins. Lancet Diabetes Endocrinol, 2019
165. Physical Plasma Membrane Perturbation Using Subcellular Optogenetics Drives Integrin-Activated Cell Migration. ACS Synth Biol, 2019
166. Light-Induced Protein Clustering for Optogenetic Interference and Protein Interaction Analysis in Drosophila S2 Cells. Biomolecules, 2019
167. Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem. Biomaterials, 2019
168. A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission. Neuron, 2019
169. Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Nat Commun, 2019
170. Blue Light Switchable Cell–Cell Interactions Provide Reversible and Spatiotemporal Control Towards Bottom-Up Tissue Engineering. Adv Biosyst, 2019
171. Enhanced intrinsic CYP3A4 activity in human hepatic C3A cells with optically controlled CRISPR/dCas9 activator complex. Integr Biol (Camb), 2018
172. Optogenetic dissection of Rac1 and Cdc42 gradient shaping. Nat Commun, 2018
173. Downregulation of basal myosin-II is required for cell shape changes and tissue invagination. EMBO J, 2018
174. Membrane dynamics induced by a PIP3 optogenetic tool. Anal Sci, 2018
175. Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control. Cell, 2018
176. RalB directly triggers invasion downstream Ras by mobilizing the Wave complex. Elife, 2018
177. Light Control of the Tet Gene Expression System in Mammalian Cells. Cell Rep, 2018
178. Optogenetic control of epithelial-mesenchymal transition in cancer cells. Sci Rep, 2018
179. A Single-Component Optogenetic System Allows Stringent Switch of Gene Expression in Yeast Cells. ACS Synth Biol, 2018
180. Spatiotemporal control of zebrafish (Danio rerio) gene expression using a light-activated CRISPR activation system. Gene, 2018
181. Optical activation of TrkA signaling. ACS Synth Biol, 2018
182. Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation. Proc Natl Acad Sci USA, 2018
183. Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis. Nat Commun, 2018
184. Independent Control over Multiple Cell Types in Space and Time Using Orthogonal Blue and Red Light Switchable Cell Interactions. Adv Sci, 2018
185. A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging. Sci Rep, 2018
186. Regulation of cell cycle progression by cell-cell and cell-matrix forces. Nat Cell Biol, 2018
187. Optogenetic inhibition of Gαq protein signaling reduces calcium oscillation stochasticity. ACS Synth Biol, 2018
188. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun, 2018
189. Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation. Sci Rep, 2018
190. A biochemical network controlling basal myosin oscillation. Nat Commun, 2018
191. Optogenetic Control of Cell Migration. Methods Mol Biol, 2018
192. Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci USA, 2018
193. Generation of Optogenetically Modified Adenovirus Vector for Spatiotemporally Controllable Gene Therapy. ACS Chem Biol, 2018
194. Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers. Sci Rep, 2018
195. Spatiotemporal Control of TGF-β Signaling with Light. ACS Synth Biol, 2017
196. Gradients of Rac1 Nanoclusters Support Spatial Patterns of Rac1 Signaling. Cell Rep, 2017
197. Real-time observation of light-controlled transcription in living cells. J Cell Sci, 2017
198. Optogenetic regulation of artificial microRNA improves H2 production in green alga Chlamydomonas reinhardtii. Biotechnol Biofuels, 2017
199. Propagating Wave of ERK Activation Orients Collective Cell Migration. Dev Cell, 2017
200. Near-Infrared Light Triggered Upconversion Optogenetic Nanosystem for Cancer Therapy. ACS Nano, 2017
201. Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase. Cell Chem Biol, 2017
202. Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1. Nucleic Acids Res, 2017
203. A single-chain photoswitchable CRISPR-Cas9 architecture for light-inducible gene editing and transcription. ACS Chem Biol, 2017
204. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017
205. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods, 2017
206. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration. J Biol Chem, 2017
207. Photo-Activatable Akt Probe - A New Tool to Study the Akt-Dependent Physiopathology of Cancer Cells. Oncol Res, 2017
208. An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis. ACS Synth Biol, 2017
209. Vesicle Docking Is a Key Target of Local PI(4,5)P2 Metabolism in the Secretory Pathway of INS-1 Cells. Cell Rep, 2017
210. A calcium- and light-gated switch to induce gene expression in activated neurons. Nat Biotechnol, 2017
211. Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts. Nat Commun, 2017
212. Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development. J Vis Exp, 2017
213. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res, 2017
214. Cell-matrix adhesion and cell-cell adhesion differentially control basal myosin oscillation and Drosophila egg chamber elongation. Nat Commun, 2017
215. Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain. Nat Methods, 2017
216. Light-Regulated Protein Kinases Based on the CRY2-CIB1 System. Methods Mol Biol, 2017
217. Optogenetic control of cellular forces and mechanotransduction. Nat Commun, 2017
218. Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics. Sci Rep, 2017
219. Optogenetic Control of Synaptic Composition and Function. Neuron, 2017
220. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun, 2017
221. A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation. ACS Chem Biol, 2016
222. Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis. Cell Rep, 2016
223. Optogenetic inhibition of apical constriction during Drosophila embryonic development. Methods Cell Biol, 2016
224. An open-hardware platform for optogenetics and photobiology. Sci Rep, 2016
225. A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol, 2016
226. Reversible optogenetic control of kinase activity during differentiation and embryonic development. Development, 2016
227. Optogenetic regulation of site-specific subtelomeric DNA methylation. Oncotarget, 2016
228. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module. Nat Commun, 2016
229. Using HEK293T Expression System to Study Photoactive Plant Cryptochromes. Front Plant Sci, 2016
230. The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress. PLoS ONE, 2016
231. Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action. J Cell Sci, 2016
232. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat Chem Biol, 2016
233. Optogenetic oligomerization of Rab GTPases regulates intracellular membrane trafficking. Nat Chem Biol, 2016
234. Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep, 2016
235. Frequency and amplitude control of cortical oscillations by phosphoinositide waves. Nat Chem Biol, 2016
236. An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis. Dev Cell, 2015
237. Predictive Spatiotemporal Manipulation of Signaling Perturbations Using Optogenetics. Biophys J, 2015
238. Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. ACS Synth Biol, 2015
239. An optogenetic system for interrogating the temporal dynamics of Akt. Sci Rep, 2015
240. Optogenetic Control of Gene Expression in Drosophila. PLoS ONE, 2015
241. Photo-activatable Cre recombinase regulates gene expression in vivo. Sci Rep, 2015
242. Optogenetic apoptosis: light-triggered cell death. Angew Chem Int Ed Engl, 2015
243. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol, 2015
244. The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells. ACS Synth Biol, 2015
245. Optogenetic control of molecular motors and organelle distributions in cells. Chem Biol, 2015
246. A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. Nat Chem Biol, 2015
247. CRISPR-Cas9-based photoactivatable transcription system. Chem Biol, 2015
248. Optogenetic control of organelle transport and positioning. Nature, 2015
249. Single-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signaling. Proc Natl Acad Sci USA, 2015
250. Benchmarking of optical dimerizer systems. ACS Synth Biol, 2014
251. Engineered UV-A light-responsive gene expression system for measuring sun cream efficacy in mammalian cell culture. J Biotechnol, 2014
252. Optogenetic engineering: light-directed cell motility. Angew Chem Int Ed Engl, 2014
253. Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration. Mol Biol Cell, 2014
254. Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling. Nat Commun, 2014
255. Reversible protein inactivation by optogenetic trapping in cells. Nat Methods, 2014
256. Bidirectional regulation of mRNA translation in mammalian cells by using PUF domains. Angew Chem Int Ed Engl, 2014
257. Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth. PLoS ONE, 2014
258. Real-time optogenetic control of intracellular protein concentration in microbial cell cultures. Integr Biol (Camb), 2014
259. Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation. Mol Cell, 2013
260. Light-inducible activation of target mRNA translation in mammalian cells. Chem Commun (Camb), 2013
261. Optical control of mammalian endogenous transcription and epigenetic states. Nature, 2013
262. Optogenetic control of PIP3: PIP3 is sufficient to induce the actin-based active part of growth cones and is regulated via endocytosis. PLoS ONE, 2013
263. Live imaging of multicolor-labeled cells in Drosophila. Development, 2013
264. Optogenetic control of transcription in zebrafish. PLoS ONE, 2012
265. Light-mediated control of DNA transcription in yeast. Methods, 2012
266. Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci USA, 2012
267. Rapid blue-light-mediated induction of protein interactions in living cells. Nat Methods, 2010
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273. Quantitative Analysis of Membrane Receptor Trafficking Manipulated by Optogenetic Tools. Methods Mol Biol, 2021
274. Engineered Cas9 extracellular vesicles as a novel gene editing tool. J Extracell Vesicles, 2022
275. Optogenetic Methods to Control Tissue Mechanics in Drosophila. Methods Mol Biol, 2022
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