Platform on Molecular Optogenetics

OptoBase is an annotated database, which aims to cover all existing non-opsin-based optogenetic switches and publications. It is meant for both expert optogeneticists, to easily keep track of the field, as well as for all researchers who find optogenetics inviting as a powerful tool to address their biological questions of interest.

Cite as: K. Kolar et al.: OptoBase: A Web Platform for Molecular Optogenetics. ACS Synth. Biol. 2018, DOI: 10.1021/acssynbio.8b00120

News & Updates (see all entries)
March 06, 2024 | Research Highlights in February

Paper of the Month February: Asymmetric oligomerization state and sequence patterning can tune multiphase condensate miscibility.

Featured Paper: A platform to induce and mature biomolecular condensates using chemicals and light.

Optogenetics is a powerful technique to manipulate biomolecular condensates. All related publications are tagged with the application "Organelle Manipulation".

Optogenetic Switches

(see the extended overview of the switches)

Click on a switch for additional information.

UV Violet Blue Cyan Green Yellow Red Far Red
300 nm 400 nm 500 nm 600 nm 700 nm

UV receptors

UVR8/COP1 UVR8/UVR8

Fluorescent proteins

PYP

Fluorescent proteins

Dronpa145K/N Dronpa145N pdDronpa1

Cobalamin-binding domains

MxCBD TtCBD

Cyanobacteriochromes

Am1_c0023g2/BAm_green